Haptoglobin anticorps (AA 180-406)

N° du produit ABIN7673380

Cet anticorps anti-Haptoglobin est un anticorps Souris Monoclonal détectant Haptoglobin dans WB et ELISA. Adapté pour Humain et Porc.

Aperçu rapide pour Haptoglobin anticorps (AA 180-406) (ABIN7673380)

Antigène: Haptoglobin (HP)

Reactivité: Humain, Porc

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp Haptoglobin est non-conjugé

Application: Western Blotting (WB), ELISA

Clone: 7C8

Détail du produit anti-Haptoglobin anticorps

Épitope: AA 180-406

Fonction: HP antibody

Purification: Protein A+G purification

Pureté: ≥95 % as determined by SDS-PAGE

Immunogène:

Immunogen sequence: 180-406aa

Immunogen: haptoglobin

Isotype: IgG2a

Information d'application

Indications d'application: WB: 1:2000 - 1:20000

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze / thaw cycles.

Stock: -20 °C

Stockage commentaire: -20°C for 12 months (Avoid repeated freeze / thaw cycles.)

Date de péremption: 12 months

Détails sur Haptoglobin

Antigène: Haptoglobin (HP)

Autre désignation: HP

Sujet:

Synonyms: Haptoglobin|Zonulin|Haptoglobin alpha chain|Haptoglobin beta chain|HP

Background: As a result of hemolysis, hemoglobin is found to accumulate in the kidney and is secreted in the urine. Haptoglobin captures, and combines with free plasma hemoglobin to allow hepatic recycling of heme iron and to prevent kidney damage. Haptoglobin also acts as an Antimicrobial, Antioxidant, has antibacterial activity and plays a role in modulating many aspects of the acute phase response. Hemoglobin/haptoglobin complexes are rapidely cleared by the macrophage CD163 scavenger receptor expressed on the surface of liver Kupfer cells through an endocytic lysosomal degradation pathway. Uncleaved haptoglogin, also known as zonulin, plays a role in intestinal permeability, allowing intercellular tight junction disassembly, and controlling the equilibrium between tolerance and immunity to non-self antigens.

Poids moléculaire: 42 kDa

ID gène: 3240

UniProt: P00738

Pathways: Transition Metal Ion Homeostasis