KCC2 anticorps

N° du produit ABIN7674503

Cet anticorps Lapin Polyclonal détecte spécifiquement KCC2 dans WB, IHC et ELISA. Il présente une réactivité envers Humain, Rat et Souris.

Aperçu rapide pour KCC2 anticorps (ABIN7674503)

Antigène: KCC2 (SLC12A5) (Solute Carrier Family 12 (Potassium-Chloride Transporter) Member 5 (SLC12A5))

Reactivité: Humain, Rat, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp KCC2 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC), ELISA

Détail du produit anti-KCC2 anticorps

Fonction: SLC12A5-Specific antibody

Purification: Immunogen affinity purified

Pureté: ≥95 % as determined by SDS-PAGE

Immunogène: solute carrier family 12(potassium-chloride transporter), member 5

Isotype: IgG

Information d'application

Indications d'application: WB: 1:500-1:5000, IHC: 1:20-1:200

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze / thaw cycles.

Stock: -20 °C

Stockage commentaire: -20°C for 12 months (Avoid repeated freeze / thaw cycles.)

Date de péremption: 12 months

Détails sur KCC2

Antigène: KCC2 (SLC12A5) (Solute Carrier Family 12 (Potassium-Chloride Transporter) Member 5 (SLC12A5))

Autre désignation: SLC12A5

Sujet:

Synonyms: Solute carrier family 12 member 5|Electroneutral potassium-chloride cotransporter 2|K-Cl cotransporter 2 (hKCC2)|Neuronal K-Cl cotransporter|SLC12A5|KCC2|KIAA1176

Background: KCC2, encoded by SLC12A5, is a neuron-specific K+-Cl-cotransporter that is essential for Cl-homeostasis and inhibitory synaptic transmission in brain. KCC2 is expressed at high levels in neurons throughout the nervous system. KCC2 deletion caused animal death. Alterations of KCC2 have been linked to neuropathic pain, temporal lobe epilepsy, and other diseases. This antibody can detect ~130 kda monomer and ~250 kDa dimer of KKC2 in brain lysate.

Poids moléculaire: 126 kDa

ID gène: 57468

UniProt: Q9H2X9