STING1 anticorps

N° du produit ABIN7674533

Cet anticorps Souris Monoclonal détecte spécifiquement dans WB, IHC et ELISA. Il présente une réactivité envers Humain.

Aperçu rapide pour STING1 anticorps (ABIN7674533)

Antigène: STING1

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Inconjugué

Application: Western Blotting (WB), Immunohistochemistry (IHC), ELISA

Clone: 1G9

Détail du produit

Fonction: STING1 antibody

Purification: Protein A+G purification

Pureté: ≥95 % as determined by SDS-PAGE

Immunogène: transmembrane protein 173

Isotype: IgG2b

Information d'application

Indications d'application: WB: 1:1000 - 1:5000, IHC: 1:100 - 1:500

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze / thaw cycles.

Stock: -20 °C

Stockage commentaire: -20°C for 12 months (Avoid repeated freeze / thaw cycles.)

Date de péremption: 12 months

Détail du antigène

Antigène: STING1

Sujet:

Synonyms: Stimulator of interferon genes protein (hSTING)|Endoplasmic reticulum interferon stimulator (ERIS)|Mediator of IRF3 activation (hMITA)|Transmembrane protein 173|STING1|ERIS|MITA|STING|TMEM173

Background: This gene encodes a five transmembrane protein that functions as a major regulator of the innate immune response to viral and bacterial infections. The encoded protein is a pattern recognition receptor that detects cytosolic nucleic acids and transmits signals that activate type I interferon responses. The encoded protein has also been shown to play a role in apoptotic signaling by associating with type II major histocompatibility complex. Mutations in this gene are the cause of infantile-onset STING-associated vasculopathy. Alternate splicing results in multiple transcript variants.

Poids moléculaire: 39 kDa

ID gène: 340061

UniProt: Q86WV6