VWF anticorps

N° du produit ABIN7674597

L’anticorps Lapin Polyclonal anti-VWF a été validé pour WB, IHC et ELISA. Il convient pour détecter VWF dans des échantillons de Humain, Rat et Souris.

Aperçu rapide pour VWF anticorps (ABIN7674597)

Antigène: VWF (Von Willebrand Factor (VWF))

Reactivité: Humain, Rat, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp VWF est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC), ELISA

Détail du produit anti-VWF anticorps

Fonction: VWF, VWFpp antibody

Purification: Immunogen affinity purified

Pureté: ≥95 % as determined by SDS-PAGE

Immunogène: von Willebrand factor

Isotype: IgG

Information d'application

Indications d'application: WB: 1:200-1:2000, IHC: 1:100-1:400

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze / thaw cycles.

Stock: -20 °C

Stockage commentaire: -20°C for 12 months (Avoid repeated freeze / thaw cycles.)

Date de péremption: 12 months

Détails sur VWF

Antigène: VWF (Von Willebrand Factor (VWF))

Autre désignation: VWF

Sujet:

Synonyms: von Willebrand factor (vWF)|von Willebrand antigen 2 Alternative names: von Willebrand antigen II|VWF|F8VWF

Background: Von Willebrand factor(vWF) is a large multimeric glycoprotein that is crucial to the hemostasis process. It supports platelet adhesion and carries factor VIII(FVIII). Deficiency of vWF results in von Willebrand disease(vWD), a common inherited bleeding disorder. The pre-pro-vWF is comprised of 2,813 amino acids(aa) which encompass a 22-aa signal peptide, a 741-aa large propeptide(vWF propeptide, vWFpp, also called von Willebrand antigen II) and 2,050 aa making up the mature vWF. The von Willebrand antigen 2 is required for multimerization of vWF and for its targeting to storage granules. This antibody raised against the N-terminal region of pre-pro-vWF recognizes von Willebrand antigen 2(75-83 kDa) and pro-vWF(309-320 kDa).

Poids moléculaire: 75 kDa, 309 kDa

UniProt: P04275