SIRPA anticorps (FineTest®700)

N° du produit ABIN7675411

L’anticorps Rat Monoclonal anti-SIRPA a été validé pour FACS. Il convient pour détecter SIRPA dans des échantillons de Souris.

Aperçu rapide pour SIRPA anticorps (FineTest®700) (ABIN7675411)

Antigène: SIRPA (Signal-Regulatory Protein alpha (SIRPA))

Reactivité: Souris

Hôte: Rat

Clonalité: Monoclonal

Conjugué: Cet anticorp SIRPA est conjugé à/à la FineTest®700

Application: Flow Cytometry (FACS)

Clone: P84

Détail du produit anti-SIRPA anticorps (FineTest®700)

Fonction: FineTest®700 Anti-Mouse CD172a/SIRPα Antibody

Isotype: IgG1, kappa

Information d'application

Indications d'application: Volume per test: 5μL. Each lot of this antibody is quality control tested by flow cytometric analysis. The amount of the reagent is suggested to be used 5 μL of antibody per test (million cells in 100 μL staining volume or per 100 μL of whole blood). Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS with 0. 1 % sodium azide, 1 %BSA, pH 7.3,

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze / thaw cycles.

Stock: 4 °C

Stockage commentaire: 2-8°C for 12 months (Avoid repeated freeze / thaw cycles.)

Date de péremption: 12 months

Détails sur SIRPA

Antigène: SIRPA (Signal-Regulatory Protein alpha (SIRPA))

Autre désignation: CD172a

Sujet:

Synonyms: BIT|CD172 antigen-like family member A|P84|PTPNS1|SHPS-1|SIRPα

Background: CD172a, also known as SIRPα, is a type I transmembrane protein with one V-set Ig-like and two C-set Ig-like domains in the extracellular portion, and two ITIM motifs and a proline-rich region in the cytoplasmic tail. CD172a is expressed by monocytes, macrophages, myeloid cells, and neuronal tissue. The phosphorylation of SIRPα ITIMs induces the recruitment and activation of the tyrosine phosphatases PTPN6 and PTPN11, resulting in the negative regulation of several biological processes. The ligands of CD172a are CD47, SP-A, and SP-D.

Poids moléculaire: 0

ID gène: 19261

UniProt: P97797