Endoglin anticorps (FineTest®700)

N° du produit ABIN7675479

Cet anticorps Rat Monoclonal détecte spécifiquement Endoglin dans FACS. Il présente une réactivité envers Souris.

Aperçu rapide pour Endoglin anticorps (FineTest®700) (ABIN7675479)

Antigène: Endoglin (ENG)

Reactivité: Souris

Hôte: Rat

Clonalité: Monoclonal

Conjugué: Cet anticorp Endoglin est conjugé à/à la FineTest®700

Application: Flow Cytometry (FACS)

Clone: MJ7-18

Détail du produit anti-Endoglin anticorps (FineTest®700)

Fonction: FineTest®700 Anti-Mouse CD105 Antibody

Isotype: IgG2a, kappa

Information d'application

Indications d'application: Volume per test: 5μL. Each lot of this antibody is quality control tested by flow cytometric analysis. The amount of the reagent is suggested to be used 5 μL of antibody per test (million cells in 100 μL staining volume or per 100 μL of whole blood). Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS with 0. 1 % sodium azide, 1 %BSA, pH 7.3,

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze / thaw cycles.

Stock: 4 °C

Stockage commentaire: 2-8°C for 12 months (Avoid repeated freeze / thaw cycles.)

Date de péremption: 12 months

Détails sur Endoglin

Antigène: Endoglin (ENG)

Autre désignation: CD105

Sujet:

Synonyms: END|Endoglin|Eng

Background: CD105 is a 90 kD homodimeric type I integral membrane glycoprotein, also known as endoglin. It is expressed on endothelial cells (especially on angiogenic endothelial cells) and upregulated by hypoxia, activated monocytes, macrophages, bone marrow stromal cells, and some cytotrophoblasts. CD105 is a receptor for TGF-β1, TGF-β3 and modulates TGF-β signaling by interacting with TGF-β receptors I and/or II. CD105 also binds other growth factors such as actvin A, BMP-2, and BMP-7. CD105 has been show to be a useful marker for identifying proliferating endothelium involved in tumor angiogenesis and can be used for tumor imaging and prognosis, and has therapeutic potential for some solid tumors and other angiogenic diseases.

Poids moléculaire: 0

ID gène: 13805

UniProt: Q63961