Ldha/Ldh anticorps

N° du produit ABIN734768

L’anticorps anti-Ldha/Ldh Polyclonal Lapin est utilisé pour la détection de Ldha/Ldh dans des échantillons de Humain, Souris et Rat. Il a été validé pour WB, IF (p) et IHC (p).

Aperçu rapide pour Ldha/Ldh anticorps (ABIN734768)

Antigène: Ldha/Ldh

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Inconjugué

Application: Western Blotting (WB), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Détail du produit

Réactivité croisée: Humain, Souris, Rat

Purification: Purified by Protein A.

Immunogène: KLH conjugated synthetic peptide derived from human LDH

Isotype: IgG

Information d'application

Indications d'application: WB(1:100-1000), IHC-P(1:100-500), IF(IHC-P)(1:50-200)

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 1 % BSA, 50 % glycerol and 0.09 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C for 12 months.

Date de péremption: 12 months

Détail du antigène

Antigène: Ldha/Ldh

Sujet:

Synonyms: Lactate Dehydrogenase, Lactate Dehydrogenase Isoenzyme V, Lactate Dehydrogenase isozyme H4, L lactate dehydrogenase A chain, Lactate dehydrogenase A, Lactate dehydrogenase A chain, LDH A, LDH heart subunit, LDH M, LDHM, LDH muscle subunit, LDH1, LDHA, PIG 19, PIG19, Proliferation inducing gene 19 protein, TRG 5, TRG5, LDHA_HUMAN.

Background: The protein encoded by this gene catalyzes the conversion of L-lactate and NAD to pyruvate and NADH in the final step of anaerobic glycolysis. The protein is found predominantly in muscle tissue and belongs to the lactate dehydrogenase family. Mutations in this gene have been linked to exertional myoglobinuria. Multiple transcript variants encoding different isoforms have been found for this gene. The human genome contains several non-transcribed pseudogenes of this gene.Lactate dehydrogenase is an enzyme present in a wide variety of organisms, including plants and animals. It catalyses the interconversion of pyruvate and lactate with concomitant interconversion of NADH and NAD+. Isoforms of the enzyme include LDH 1 (4H) in the heart, LDH 2 (3H1M) in the reticuloendothelial system, LDH 3 (2H2M) in the lungs, LDH 4 (1H3M) in the kidneys and LDH 5 (4M) in the liver and striated muscle. The M and H subunits are encoded by two different genes.

ID gène: 3939