Prostaglandin E Synthase anticorps (PE-Cy7)

N° du produit ABIN735801

Cet anticorps anti-Prostaglandin E Synthase est un anticorps Lapin Polyclonal détectant Prostaglandin E Synthase dans WB. Adapté pour Humain, Rat, Souris et Cobaye.

Aperçu rapide pour Prostaglandin E Synthase anticorps (PE-Cy7) (ABIN735801)

Antigène: Prostaglandin E Synthase (PTGES)

Reactivité: Humain, Rat, Souris, Cobaye

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Prostaglandin E Synthase est conjugé à/à la PE-Cy7

Application: Western Blotting (WB)

Détail du produit anti-Prostaglandin E Synthase anticorps (PE-Cy7)

Réactivité croisée: Humain

Homologie: Mouse,Rat,Pig,Guinea Pig

Purification: Purified by Protein A.

Immunogène: KLH conjugated synthetic peptide derived from human PTGEs

Isotype: IgG

Information d'application

Indications d'application: FCM(1:100-500)
Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Date de péremption: 12 months

Détails sur Prostaglandin E Synthase

Antigène: Prostaglandin E Synthase (PTGES)

Autre désignation: PTGEs

Sujet:

Synonyms: PGES, MPGES, PIG12, PP102, PP1294, MGST-IV, MGST1L1, TP53I12, mPGES-1, MGST1-L1, Prostaglandin E synthase, Microsomal glutathione S-transferase 1-like 1, Microsomal prostaglandin E synthase 1, p53-induced gene 12 protein, PTGES, MPGES1

Background: Prostaglandin E synthase catalyses conversion of COX derived PGH2 to PGE2. It is a member of the MAPEG family. It may contribute to the pathogenesis of collagen induced arthritis and mediate acute pain during inflammatory responses.The protein encoded by this gene is a glutathione-dependent prostaglandin E synthase. The expression of this gene has been shown to be induced by proinflammatory cytokine interleukin 1 beta (IL1B). Its expression can also be induced by tumor suppressor protein TP53, and may be involved in TP53 induced apoptosis. Knockout studies in mice suggest that this gene may contribute to the pathogenesis of collagen-induced arthritis and mediate acute pain during inflammatory responses.

Poids moléculaire: 17kDa

ID gène: 9536

UniProt: O14684