TGM3 anticorps (AA 601-693)

N° du produit ABIN736253

Il existe 1 publication pour ce produit. L’anticorps anti-TGM3 Polyclonal Lapin est utilisé pour la détection de TGM3 dans des échantillons de Souris et Rat. Il a été validé pour ELISA, IF (cc), IF (p), IHC (fro) et IHC (p).

Aperçu rapide pour TGM3 anticorps (AA 601-693) (ABIN736253)

Antigène: TGM3 (Transglutaminase 3 (E Polypeptide, Protein-Glutamine-gamma-Glutamyltransferase) (TGM3))

Reactivité: Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp TGM3 est non-conjugé

Application: ELISA, Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Détail du produit anti-TGM3 anticorps

Épitope: AA 601-693

Réactivité croisée: Souris, Rat

Homologie: Human,Dog,Cow,Horse,Rabbit

Purification: Purified by Protein A.

Immunogène: KLH conjugated synthetic peptide derived from human TGM3

Isotype: IgG

Information d'application

Indications d'application: ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Date de péremption: 12 months

Références pour anticorps anti-TGM3 (ABIN736253)

Kawabe, Takano, Moriyama, Nakamura: "Transglutaminases Derived from Astrocytes Accelerate Amyloid β Aggregation." dans: Neurochemical research, Vol. 42, Issue 8, pp. 2384-2391, (2017) (PubMed).

Détails sur TGM3

Antigène: TGM3 (Transglutaminase 3 (E Polypeptide, Protein-Glutamine-gamma-Glutamyltransferase) (TGM3))

Autre désignation: TGM3

Sujet:

Synonyms: TGE, Protein-glutamine gamma-glutamyltransferase E, Transglutaminase E, TG(E), TGase E, Transglutaminase-3, TGase-3, TGM3

Background: Catalyzes the calcium-dependent formation of isopeptide cross-links between glutamine and lysine residues in various proteins, as well as the conjugation of polyamines to proteins. Involved in the formation of the cornified envelope (CE), a specialized component consisting of covalent cross-links of proteins beneath the plasma membrane of terminally differentiated keratinocytes. Catalyzes small proline-rich proteins (SPRR1 and SPRR2) and LOR cross-linking to form small interchain oligomers, which are further cross-linked by TGM1 onto the growing CE scaffold (By similarity). In hair follicles, involved in cross-linking structural proteins to hardening the inner root sheath.

ID gène: 7053

UniProt: Q08188