KLF2/4 anticorps (AA 415-513)

N° du produit ABIN737121

Détail du produit anti-KLF2/4 anticorps

Antigène: KLF2/4 (Kruppel-Like Factor 2/4 (KLF2/4))

Épitope: AA 415-513

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp KLF2/4 est non-conjugé

Application: Western Blotting (WB), Flow Cytometry (FACS), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), ELISA, Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Specificité: This antibody may crossreact with KLF2 due to high sequence similarity.

Réactivité croisée: Humain, Souris, Rat

Homologie: Cow,Sheep,Pig,Horse,Chicken,Guinea Pig

Purification: Purified by Protein A.

Immunogène: KLH conjugated synthetic peptide derived from human KLF4

Isotype: IgG

Information d'application

Indications d'application: WB 1:300-5000
ELISA 1:500-1000
FCM 1:20-100
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Date de péremption: 12 months

Références pour anticorps anti-KLF2/4 (ABIN737121)

Verma, Lovren, Pan, Yanagawa, Deb, Karkhanis, Quan, Teoh, Feder-Elituv, Moussa, Souza, Fremes: "Pedicled no-touch saphenous vein graft harvest limits vascular smooth muscle cell activation: the PATENT saphenous vein graft study." dans: European journal of cardio-thoracic surgery : official journal of the European Association for Cardio-thoracic Surgery, Vol. 45, Issue 4, pp. 717-25, (2014) (PubMed).

El-Sayed, Zhang, Zhang, Liu, Abbott, Zhang, Li: "Pluripotent state induction in mouse embryonic fibroblast using mRNAs of reprogramming factors." dans: International journal of molecular sciences, Vol. 15, Issue 12, pp. 21840-64, (2014) (PubMed).

Lovren, Pan, Quan, Singh, Shukla, Gupta, Steer, Ingram, Gupta, Al-Omran, Teoh, Marsden, Verma: "MicroRNA-145 targeted therapy reduces atherosclerosis." dans: Circulation, Vol. 126, Issue 11 Suppl 1, pp. S81-90, (2012) (PubMed).

Détails sur KLF2/4

Antigène: KLF2/4 (Kruppel-Like Factor 2/4 (KLF2/4))

Abstract: KLF2/4 Produits

Sujet:

Synonyms: EZF, GKLF, Krueppel-like factor 4, Epithelial zinc finger protein EZF, Gut-enriched krueppel-like factor, KLF4

Background: Transcription factor, can act both as activator and as repressor. Binds the 5'-CACCC-3' core sequence. Binds to the promoter region of its own gene and can activate its own transcription. Regulates the expression of key transcription factors during embryonic development. Plays an important role in maintaining embryonic stem cells, and in preventing their differentiation. Required for establishing the barrier function of the skin and for postnatal maturation and maintenance of the ocular surface. Involved in the differentiation of epithelial cells and may also function in skeletal and kidney development. Contributes to the down-regulation of p53/TP53 transcription.

ID gène: 9314

UniProt: O43474