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EBOV VP40 anticorps

Cet anticorps Souris Monoclonal détecte spécifiquement EBOV VP40 dans ELISA, WB et BP. Il présente une réactivité envers Ebola Virus.
N° du produit ABIN7794821

Aperçu rapide pour EBOV VP40 anticorps (ABIN7794821)

Antigène

EBOV VP40 (Ebola Virus Matrix protein VP40 (EBOV VP40))

Reactivité

  • 4
  • 1
Ebola Virus

Hôte

  • 5
Souris

Clonalité

  • 5
Monoclonal

Conjugué

  • 5
Cet anticorp EBOV VP40 est non-conjugé

Application

ELISA, Western Blotting (WB), Blocking Peptide (BP)

Clone

EB-977
  • Fonction

    Anti-Ebola Virus, VP40 (EB-977)

    Specificité

    Anti-Ebola Virus (Clone EB-977) has known reactivity for the viral antigen VP40 of Sudan and Zaire strains (reacts with VLPs). Background Ebola virus is a highly infectious and deadly enveloped RNA virus that belongs to the Filoviridae family. It causes severe and often fatal hemorrhagic fever in humans and non-human primates. Ebola is considered endemic in certain parts of Africa where outbreaks have occurred in various countries such as the Democratic Republic of Congo, Sudan, Guinea, Libera, Sierra Leone, and Uganda. VP40 is a matrix protein of Ebola virus that is the most abundantly expressed viral protein during infection. The protein plays an important role in viral assembly and budding with exogenous expression of VP40 being sufficient to induce the formation of viral-like particles. VP40 can oligomerize and the different oligomeric states have distinct functions during infection the octameric confirmation plays a critical role in regulating viral transcription while hexamers localize to the plasma membrane. Because of its critical role in the viral life cycle and abundance, VP40 has been used in diagnostic testing as well as potential therapeutics.

    Purification

    This monoclonal antibody is purified by protein A chromatography or sequential differential precipitations.

    Pureté

    ≥90 %

    Isotype

    IgG2b
  • Indications d'application

    ELISA: 1:20 - 1:200,WB

    Restrictions

    For Research Use only
  • Concentration

    1 μg/mL

    Buffer

    Formulated in 0.01 M phosphate buffered saline, pH 7.2 and contains 0.1 % sodium azide. Due to inherent biochemical properties of antibodies, certain products may be prone to precipitation over time. Precipitation may be removed by aseptic centrifugation and/or filtration.

    Agent conservateur

    Sodium azide

    Précaution d'utilisation

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    Stock

    4 °C

    Stockage commentaire

    This purified antibody is stable when stored at 2-8°C. Do not freeze.
  • Antigène

    EBOV VP40 (Ebola Virus Matrix protein VP40 (EBOV VP40))

    Autre désignation

    Ebola Virus, VP40

    Classe de substances

    Viral Protein

    Sujet

    EB,
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