Influenza Virus Nucleoprotein anticorps (Influenza A Virus)

N° du produit ABIN7795017

L’anticorps anti-Influenza Virus Nucleoprotein Monoclonal Souris est utilisé pour la détection de Influenza Virus Nucleoprotein dans des échantillons de Influenza A Virus. Il a été validé pour ELISA, IF et IHC.

Aperçu rapide pour Influenza Virus Nucleoprotein anticorps (Influenza A Virus) (ABIN7795017)

Antigène: Influenza Virus Nucleoprotein (IV NP)

Reactivité: Influenza A Virus

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Inconjugué

Application: ELISA, Immunofluorescence (IF), Immunohistochemistry (IHC)

Clone: IA-3808

Détail du produit

Fonction: Anti-Influenza A, Nucleocapsid

Specificité: Anti-Influenza A, Nucleoprotein (Clone IA-3808) is reactive with >50 separate isolates from H1 through H14. Background There are four types of Influenza (flu) viruses type A, B, C, and D. Influenza A and B viruses are routinely spread in people and other mammals, while also known for seasonal flu epidemics each year. Influenza A is the genus Alphainfluenzavirus of the virus family Orthomyxoviridae. Influenza A is classified into two main protein subtypes, hemagglutinin (HA) and neuraminidase (NA), located on the surface of the virus. Breaking down the proteins further, there are 18 hemagglutinin subtypes and 11 different neuraminidase subtypes1. Influenza A can be even further classified into specific clades (also known as groups) and sub-clades (also known as sub-groups) based on similarity of their HA/NA gene sequences1. The Nucleocapsid protein or nucleoprotein (NP) of the influenza virus A negative-strand RNA?s primary function is to encapsulate the virus genome for the purpose of RNA transcription, replication and packaging2. Specifically, NP is the most abundant viral protein in infected cells2, therefore the NP can be and has been used for anti-influenza drug development3. The NP of influenza A and B viruses share up to 38 % of their amino acid sequence, indicating region functionality differences at the amino acid level4.

Purification: This monoclonal antibody is purified from ascites fluid or culture medium by protein A chromatography or sequential differential precipitations.

Pureté: >90 % monomer by analytical SEC and SDS-Page

Isotype: IgG2a

Information d'application

Indications d'application: ELISA Recommended starting range 1:20-1:200 IF Recommended starting range 1:10-1:50 IHC

Restrictions: For Research Use only

Stockage

Concentration: 1 μg/mL

Buffer: This monoclonal antibody is aseptically packaged and formulated in 0.01 M phosphate buffered saline, pH 7.2 and contains 0.1 % sodium azide. Due to inherent biochemical properties of antibodies, certain products may be prone to precipitation over time. Precipitation may be removed by aseptic centrifugation and/or filtration.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C

Stockage commentaire: This product contains no stabilizing proteins and should be stored at 2-8°C until ready to use.

Détail du antigène

Antigène: Influenza Virus Nucleoprotein (IV NP)

Autre désignation: Influenza A Nucleocapsid

Classe de substances: Influenza Protein

Sujet: Common flu NP, Influenza A virus NP, NP, Nucleocapsid protein, Nucleoprotein, Protein N, Seasonal Influenza A (H1N1) Nucleocapsid Protein,