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Recombinant MS4A1 (Rituximab Biosimilar) anticorps

Cet anticorps Souris Monoclonal détecte spécifiquement MS4A1 (Rituximab Biosimilar) dans FACS et in vivo. Il présente une réactivité envers Humain.
N° du produit ABIN7795085

Aperçu rapide pour Recombinant MS4A1 (Rituximab Biosimilar) anticorps (ABIN7795085)

Antigène

MS4A1 (Rituximab Biosimilar)

Type d'anticorp

Recombinant Antibody

Reactivité

  • 7
  • 2
  • 2
Humain

Hôte

  • 3
  • 2
  • 1
  • 1
Souris

Clonalité

  • 4
  • 3
Monoclonal

Conjugué

  • 7
Cet anticorp MS4A1 (Rituximab Biosimilar) est non-conjugé

Application

  • 6
  • 2
  • 1
  • 1
  • 1
  • 1
Flow Cytometry (FACS), In vivo Studies (in vivo)

Classe de qualité

Research Grade
  • Expression System

    Mammalian cells

    Fonction

    Rituximab Biosimilar, Endotoxin 0.05 EU/mg

    Attributs du produit

    B-lymphocyte antigen CD20 encoded by the MS4A1 gene is an activated-glycosylated phosphoprotein on the surface of all B-cells. The function of the membrane protein is to stimulate B-cell immune response, specifically against T-independent antigens though its natural ligand remains unknown. CD20 is important for the development and differentiation of B-cells into plasma cells. CD20 belongs to the membrane-spanning 4A family with common structural features, similar intron/exon splice boundaries, and unique expression patterns among hematopoietic cells and nonlymphoid tissues. Rituximab, a chimeric anti-CD20 monoclonal antibody, destroys B cells and is used to treat diseases with excessive numbers of B cells, overactive B cells, or dysfunctional B cells, such as many lymphomas, leukemias, transplant rejection, and autoimmune disorders.

    Purification

    Protein A or G affinity column

    Pureté

    >95 % by reducing SDS-PAGE

    niveau d'endotoxine

    Less than 0.5 EU/mg of protein as determined by LAL method

    Immunogène

    Human lymphoblastoid cell line SB
  • Indications d'application

    Optimal working dilution should be determined by the investigator.

    Restrictions

    For Research Use only
  • Format

    Liquid

    Concentration

    > 3 mg/mL

    Stock

    4 °C,-20 °C

    Stockage commentaire

    Short time 2 to 8°C as supplied. Long time -20°C to -70°C as supplied.
  • Antigène

    MS4A1 (Rituximab Biosimilar)

    Autre désignation

    Rituximab Biosimilar

    Classe de substances

    Biosimilar
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