Recombinant CD4 (Clenoliximab Biosimilar) anticorps

N° du produit ABIN7795103

Cet anticorps Souris Monoclonal détecte spécifiquement CD4 (Clenoliximab Biosimilar) dans FACS et in vivo. Il présente une réactivité avec des échantillons de Humain.

Aperçu rapide pour Recombinant CD4 (Clenoliximab Biosimilar) anticorps (ABIN7795103)

Antigène: CD4 (Clenoliximab Biosimilar)

Type d'anticorp: Recombinant Antibody

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Inconjugué

Application: Flow Cytometry (FACS), In vivo Studies (in vivo)

Classe de qualité: Research Grade

Détail du produit

Expression System: Mammalian cells

Fonction: Clenoliximab Biosimilar, CD4 Monoclonal Antibody

Attributs du produit: Clenoliximab Biosimilar uses the same protein sequences as the therapeutic antibody clenoliximab. Clenoliximab is a chimeric monoclonal antibody from Macaca irus against CD4 which acts as an immunomodulator. It has investigated for the treatment of rheumatoid arthritis. Clenoliximab is a macaque-human chimeric monoclonal antibody (immunoglobulin G4)that binds specifically to the CD4 receptor present on T-lympocytes (Helper T lymphocytes). CD-4 lymphocytes are implicated in the pathogenesis of rheumatoid arthritis (RA). Clenoliximab coats the CD4 T-lymphocytes and thus down-modulates the CD4 T-lympocytes in a dose and concentration-dependent manner without decreasing the amount of CD4 T-lympocytes in circulation.

Purification: Protein A or G affinity column

Pureté: >95 % by reducing SDS-PAGE

niveau d'endotoxine: < 1 EU per 1 mg of the protein by the LAL method

Immunogène: Human CD4

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: > 3 mg/mL

Stock: 4 °C,-20 °C

Stockage commentaire: Short time 2 to 8°C as supplied. Long time -20°C to -70°C as supplied.

Détail du antigène

Antigène: CD4 (Clenoliximab Biosimilar)

Autre désignation: Clenoliximab Biosimilar

Classe de substances: Biosimilar