Recombinant IL2RA (Daclizumab Biosimilar) anticorps
Aperçu rapide pour Recombinant IL2RA (Daclizumab Biosimilar) anticorps (ABIN7795104)
Antigène
Type d'anticorp
Reactivité
Hôte
Clonalité
Conjugué
Application
Classe de qualité
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Expression System
- Mammalian cells
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Fonction
- Daclizumab Biosimilar, CD25 Monoclonal Antibody
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Attributs du produit
- Daclizumab Biosimilar uses the same protein sequences as the therapeutic antibody daclizumab. Humanized IgG1 Mab that binds to the human interleukin-2 receptor (anti-Tac or anti-CD25). Daclizumab is a composite of human (90 % ) and murine (10 %) antibody sequences. The human sequences were derived from the constant domains of human IgG1 and the variable framework regions of the Eu myeloma antibody. The murine sequences were derived from the complementarity-determining regions of a murine anti-Tac antibody. Daclizumab binds with high-affinity to the Tac subunit of the high-affinity IL-2 receptor complex and inhibits IL-2 binding. The IL-2 receptor (Tac) subunit is expressed on activated but not resting lymphocytes.
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Purification
- Protein A or G affinity column
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Pureté
- >95 % by reducing SDS-PAGE
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niveau d'endotoxine
- < 1 EU per 1 mg of the protein by the LAL method
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Immunogène
- Human CD25
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Indications d'application
- Optimal working dilution should be determined by the investigator.
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- > 3 mg/mL
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Stock
- 4 °C,-20 °C
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Stockage commentaire
- Short time 2 to 8°C as supplied. Long time -20°C to -70°C as supplied.
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- IL2RA (Daclizumab Biosimilar)
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Autre désignation
- Daclizumab Biosimilar
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Classe de substances
- Biosimilar
Antigène
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