Recombinant TNFRSF10B (Drozitumab Biosimilar) anticorps
Aperçu rapide pour Recombinant TNFRSF10B (Drozitumab Biosimilar) anticorps (ABIN7795105)
Antigène
Type d'anticorp
Reactivité
Hôte
Clonalité
Conjugué
Application
Classe de qualité
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Expression System
- Mammalian cells
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Fonction
- Drozitumab Biosimilar, TRAIL Monoclonal Antibody
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Attributs du produit
- Drozitumab Biosimilar uses the same protein sequences as the therapeutic antibody drozitumab. Drozitumab is a human monoclonal antibody in development for the treatment of cancers. It targets Tumour Necrosis Factor Related Apoptosis-inducing Ligand (TRAIL), whose receptors are found on the surface of many types of malignant cells. Although drozitumab was studied in phase II trials for treating chondrosarcoma, colorectal cancer, non-Hodgkin lymphoma, and non-small cell lung cancer, development has been halted due to lack of clinical response.
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Purification
- Protein A or G affinity column
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Pureté
- >95 % by reducing SDS-PAGE
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niveau d'endotoxine
- < 1 EU per 1 mg of the protein by the LAL method
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Immunogène
- Human TRAIL
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Indications d'application
- Optimal working dilution should be determined by the investigator.
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- > 3 mg/mL
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Stock
- 4 °C,-20 °C
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Stockage commentaire
- Short time 2 to 8°C as supplied. Long time -20°C to -70°C as supplied.
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- TNFRSF10B (Drozitumab Biosimilar)
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Autre désignation
- Drozitumab Biosimilar
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Classe de substances
- Biosimilar
Antigène
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