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Recombinant CD22 (Epratuzumab Biosimilar) anticorps

L’anticorps Humanized Monoclonal anti-CD22 (Epratuzumab Biosimilar) a été validé pour FACS et in vivo. Il convient pour détecter CD22 (Epratuzumab Biosimilar) dans des échantillons de Humain.
N° du produit ABIN7795107

Aperçu rapide pour Recombinant CD22 (Epratuzumab Biosimilar) anticorps (ABIN7795107)

Antigène

CD22 (Epratuzumab Biosimilar)

Type d'anticorp

Recombinant Antibody

Reactivité

  • 4
  • 2
  • 2
Humain

Hôte

  • 2
  • 1
  • 1
Humanized

Clonalité

  • 2
  • 2
Monoclonal

Conjugué

  • 4
Cet anticorp CD22 (Epratuzumab Biosimilar) est non-conjugé

Application

  • 3
  • 2
  • 2
  • 1
Flow Cytometry (FACS), In vivo Studies (in vivo)

Classe de qualité

Research Grade
  • Expression System

    Mammalian cells

    Fonction

    Epratuzumab Biosimilar, CD22 Monoclonal Antibody

    Attributs du produit

    Epratuzumab Biosimilar uses the same protein sequences as the therapeutic antibody epratuzumab. Epratuzumab is a humanized monoclonal antibody derived from the murine IG2a monoclonal antibody, LL2 (EPB-2). This agent may subsequently be well matched for use in oncology and the treatment of inflammatory autoimmune disorders, such as lupus. Epratuzumab is a recombinant, humanized monoclonal antibody directed against CD22, a cell surface glycoprotein present on mature B-cells and on many types of malignant B-cells. It binds with high specificity to normal B-cells and B-cell tumors at the third Ig-like domain of CD22. After binding to CD22, epratuzumab's predominant antitumor activity appears to be mediated through antibody-dependent cellular cytotoxicity (ADCC).

    Purification

    Protein A or G affinity column

    Pureté

    >95 % by reducing SDS-PAGE

    niveau d'endotoxine

    < 1 EU per 1 mg of the protein by the LAL method

    Immunogène

    Human CD22
  • Indications d'application

    Optimal working dilution should be determined by the investigator.

    Restrictions

    For Research Use only
  • Format

    Liquid

    Concentration

    > 3 mg/mL

    Stock

    4 °C,-20 °C

    Stockage commentaire

    Short time 2 to 8°C as supplied. Long time -20°C to -70°C as supplied.
  • Antigène

    CD22 (Epratuzumab Biosimilar)

    Autre désignation

    Epratuzumab Biosimilar

    Classe de substances

    Biosimilar
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