L’anticorps Humanized Monoclonal anti-CD22 (Epratuzumab Biosimilar) a été validé pour FACS et in vivo. Il convient pour détecter CD22 (Epratuzumab Biosimilar) dans des échantillons de Humain.
N° du produit ABIN7795107
Aperçu rapide pour Recombinant CD22 (Epratuzumab Biosimilar) anticorps (ABIN7795107)
Antigène
CD22 (Epratuzumab Biosimilar)
Type d'anticorp
Recombinant Antibody
Reactivité
Humain
Hôte
Humanized
Clonalité
Monoclonal
Conjugué
Cet anticorp CD22 (Epratuzumab Biosimilar) est non-conjugé
Application
Flow Cytometry (FACS), In vivo Studies (in vivo)
Classe de qualité
Research Grade
Expression System
Mammalian cells
Fonction
Epratuzumab Biosimilar, CD22 Monoclonal Antibody
Attributs du produit
Epratuzumab Biosimilar uses the same protein sequences as the therapeutic antibody epratuzumab. Epratuzumab is a humanized monoclonal antibody derived from the murine IG2a monoclonal antibody, LL2 (EPB-2). This agent may subsequently be well matched for use in oncology and the treatment of inflammatory autoimmune disorders, such as lupus. Epratuzumab is a recombinant, humanized monoclonal antibody directed against CD22, a cell surface glycoprotein present on mature B-cells and on many types of malignant B-cells. It binds with high specificity to normal B-cells and B-cell tumors at the third Ig-like domain of CD22. After binding to CD22, epratuzumab's predominant antitumor activity appears to be mediated through antibody-dependent cellular cytotoxicity (ADCC).