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Recombinant EGFR (Matuzumab Biosimilar) anticorps

Cet anticorps Humanized Monoclonal détecte spécifiquement EGFR (Matuzumab Biosimilar) dans FACS et in vivo. Il présente une réactivité envers Humain.
N° du produit ABIN7795112

Aperçu rapide pour Recombinant EGFR (Matuzumab Biosimilar) anticorps (ABIN7795112)

Antigène

EGFR (Matuzumab Biosimilar)

Type d'anticorp

Recombinant Antibody

Reactivité

Humain

Hôte

  • 1
  • 1
  • 1
  • 1
  • 1
Humanized

Clonalité

  • 3
  • 2
Monoclonal

Conjugué

  • 5
Cet anticorp EGFR (Matuzumab Biosimilar) est non-conjugé

Application

  • 4
  • 3
  • 3
  • 3
  • 3
  • 3
Flow Cytometry (FACS), In vivo Studies (in vivo)

Classe de qualité

Research Grade
  • Expression System

    Mammalian cells

    Fonction

    Matuzumab Biosimilar, EGFR Monoclonal Antibody

    Attributs du produit

    Matuzumab Biosimilar uses the same protein sequences as the therapeutic antibody matuzumab. Matuzumab is a humanized monoclonal antibody used in cancer treatment. It has a high affinity for EGFR (epithelial growth factor receptor), frequently associated with the growth of blood vessels in malignancy, facilitating tumor growth and survival. Matuzumab binds the epidermal growth factor receptor (EGFR) with high affinity, competitively blocking natural ligand binding and blocking receptor-mediated downstream signalling, resulting in impaired tumor cell proliferation. Matuzumab (EMD-72000) is a humanized IgG1 MAb that not only binds with high specificity and affinity to EGFR, but also modulates antibody-dependent cellular cytotoxicity (ADCC).

    Purification

    Protein A or G affinity column

    Pureté

    >95 % by reducing SDS-PAGE

    niveau d'endotoxine

    < 1 EU per 1 mg of the protein by the LAL method

    Immunogène

    Human EGFR
  • Indications d'application

    Optimal working dilution should be determined by the investigator.

    Restrictions

    For Research Use only
  • Format

    Liquid

    Concentration

    > 3 mg/mL

    Stock

    4 °C,-20 °C

    Stockage commentaire

    Short time 2 to 8°C as supplied. Long time -20°C to -70°C as supplied.
  • Antigène

    EGFR (Matuzumab Biosimilar)

    Autre désignation

    Matuzumab Biosimilar

    Classe de substances

    Biosimilar
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