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Recombinant CD3E (Muromonab Biosimilar) anticorps

Cet anticorps Souris Monoclonal détecte spécifiquement CD3E (Muromonab Biosimilar) dans FACS et in vivo. Il présente une réactivité envers Humain.
N° du produit ABIN7795115

Aperçu rapide pour Recombinant CD3E (Muromonab Biosimilar) anticorps (ABIN7795115)

Antigène

CD3E (Muromonab Biosimilar)

Type d'anticorp

Recombinant Antibody

Reactivité

  • 2
  • 1
Humain

Hôte

  • 1
  • 1
  • 1
Souris

Clonalité

  • 2
  • 1
Monoclonal

Conjugué

  • 3
Cet anticorp CD3E (Muromonab Biosimilar) est non-conjugé

Application

Flow Cytometry (FACS), In vivo Studies (in vivo)

Classe de qualité

Research Grade
  • Expression System

    Mammalian cells

    Fonction

    Muromonab Biosimilar, CD3 Monoclonal Antibody

    Attributs du produit

    Muromonab Biosimilar uses the same protein sequences as the therapeutic antibody muromonab (OKT3). Muromonab (OKT-3) is a monoclonal anti-CD3 antibody used as immunosuppressive therapy in kidney, heart, and liver transplant patients. Murine monoclonal antibody specific to CD3 T-cell lymphocyte antigens. More specifically it is a purified murine (mouse) monoclonal antibody, directed against the CD3 (T3) receptor on the surface of human T-cells (T-lymphocytes) cultured using the murine ascites method. Muromonab is 93 % monomeric immune globulin G type 2a (IgG2a). Muromonab binds to the T-cell surface glycoprotein CD3 epsilon chain. It appears to kill CD-3 positive cells by inducing Fc mediated apoptosis, antibody mediated cytotoxicity and complement-dependent cytotoxicity.

    Purification

    Protein A or G affinity column

    Pureté

    >95 % by reducing SDS-PAGE

    niveau d'endotoxine

    < 1 EU per 1 mg of the protein by the LAL method

    Immunogène

    Human CD3
  • Indications d'application

    Optimal working dilution should be determined by the investigator.

    Restrictions

    For Research Use only
  • Format

    Liquid

    Concentration

    > 3 mg/mL

    Stock

    4 °C,-20 °C

    Stockage commentaire

    Short time 2 to 8°C as supplied. Long time -20°C to -70°C as supplied.
  • Antigène

    CD3E (Muromonab Biosimilar)

    Autre désignation

    Muromonab Biosimilar

    Classe de substances

    Biosimilar
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