Cet anticorps Souris Monoclonal détecte spécifiquement VEGFA (Brolucizumab Biosimilar) dans FACS et in vivo. Il présente une réactivité avec des échantillons de Humain.
Brolucizumab Biosimilar uses the same protein sequences as the therapeutic antibody brolucizumab. Brolucizumab is a monoclonal antibody indicated to treat neovascular age related macular degeneration. Brolucizumab is a vascular endothelial growth factor (VEGF) inhibitor which targets the major VEGF-A isoforms: VEGF110, VEGF121, and VEGF165. Inhibition of these VEGF-A isoforms reduce proliferation of endothelial cells, vascularization of the tissue, and permeability of the vasculature.
Purification
Protein A or G affinity column
Pureté
>95 % by reducing SDS-PAGE
niveau d'endotoxine
< 1 EU per 1 mg of the protein by the LAL method
Immunogène
Human VEGF-A
Indications d'application
Optimal working dilution should be determined by the investigator.
Restrictions
For Research Use only
Format
Liquid
Concentration
> 3 mg/mL
Stock
4 °C,-20 °C
Stockage commentaire
Short time 2 to 8°C as supplied. Long time -20°C to -70°C as supplied.