Cet anticorps Souris Monoclonal détecte spécifiquement Etanercept Biosimilar dans FACS et in vivo. Il présente une réactivité avec des échantillons de Humain.
Aperçu rapide pour Recombinant Etanercept Biosimilar anticorps (ABIN7795136)
Antigène
Etanercept Biosimilar
Type d'anticorp
Recombinant Antibody
Reactivité
Humain
Hôte
Souris
Clonalité
Monoclonal
Application
Flow Cytometry (FACS), In vivo Studies (in vivo)
Classe de qualité
Research Grade
Expression System
Mammalian cells
Fonction
Etanercept Biosimilar
Attributs du produit
What is research grade Etanercept biosimilar? Research grade Etanercept biosimilar has the same amino acid sequence as Etanercept (trade name Enbrel), a fusion protein of the soluble TNF receptor 2 and a Fc fragment (human IgG1 isotype). Etanercept can be used to treat autoimmune diseases by interfering with tumor necrosis factor (TNF), a soluble inflammatory cytokine, by acting as a TNF inhibitor. TNF alpha is the "master regulator" of the inflammatory (immune) response in many organ systems. Autoimmune diseases are caused by an overactive immune response. Etanercept has the potential to treat these diseases by inhibiting TNF alpha. Etanercept binds to TNF alpha and decreases its role in disorders involving excess inflammation in humans and other animals, including autoimmune diseases such as ankylosing spondylitis, juvenile rheumatoid arthritis, psoriasis, psoriatic arthritis, rheumatoid arthritis, and, potentially, in a variety of other disorders mediated by excess TNF alpha.
Purification
Protein A or G affinity column
Pureté
>95 % by reducing SDS-PAGE
niveau d'endotoxine
< 1 EU per 1 mg of the protein by the LAL method
Indications d'application
Optimal working dilution should be determined by the investigator.
Restrictions
For Research Use only
Format
Liquid
Concentration
> 3 mg/mL
Stock
4 °C,-20 °C
Stockage commentaire
Short time 2 to 8°C as supplied. Long time -20°C to -70°C as supplied.