Recombinant IL-4RA (Dupilumab Biosimilar) anticorps
Aperçu rapide pour Recombinant IL-4RA (Dupilumab Biosimilar) anticorps (ABIN7795141)
Antigène
Type d'anticorp
Reactivité
Hôte
Clonalité
Conjugué
Application
Classe de qualité
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Expression System
- Mammalian cells
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Fonction
- Dupilumab Biosimilar, Human IL4R alpha Monoclonal Antibody
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Attributs du produit
- What is dupilumab biosimilar research grade? Dupilumab is a monoclonal antibody blocking interleukin 4 and interleukin 13, used for allergic diseases such as eczema (atopic dermatitis), asthma and nasal polyps which result in chronic sinusitis. It is also used for the treatment of eosinophilic esophagitis and prurigo nodularis. Dupilumab binds to the alpha subunit of the interleukin-4 receptor (IL-4Ra), making it a receptor antagonist. Through blockade of IL-4Ra, dupilumab modulates signaling of both the interleukin 4 and interleukin 13 pathways. Dupilumab biosimilar uses the same protein sequences as the therapeutic antibody dupilumab.
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Purification
- Protein A or G affinity column
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Pureté
- >95 % by reducing SDS-PAGE
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niveau d'endotoxine
- < 1 EU per 1 mg of the protein by the LAL method
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Immunogène
- Human IL4R alpha
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Indications d'application
- Optimal working dilution should be determined by the investigator.
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- > 3 mg/mL
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Stock
- 4 °C,-20 °C
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Stockage commentaire
- Short time 2 to 8°C as supplied. Long time -20°C to -70°C as supplied.
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- IL-4RA (Dupilumab Biosimilar)
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Autre désignation
- Dupilumab Biosimilar
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Classe de substances
- Biosimilar
Antigène
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