Recombinant PCSK9 (Evolocumab Biosimilar) anticorps

N° du produit ABIN7795143

L’anticorps anti-PCSK9 (Evolocumab Biosimilar) Monoclonal Souris est utilisé pour la détection de PCSK9 (Evolocumab Biosimilar) dans des échantillons de Humain. Il a été validé pour FACS et in vivo.

Aperçu rapide pour Recombinant PCSK9 (Evolocumab Biosimilar) anticorps (ABIN7795143)

Antigène: PCSK9 (Evolocumab Biosimilar)

Type d'anticorp: Recombinant Antibody

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp PCSK9 (Evolocumab Biosimilar) est non-conjugé

Application: Flow Cytometry (FACS), In vivo Studies (in vivo)

Classe de qualité: Research Grade

Détail du produit anti-PCSK9 (Evolocumab Biosimilar) anticorps

Expression System: Mammalian cells

Fonction: Evolocumab Biosimilar, Human PCSK9 Monoclonal Antibody

Attributs du produit: What is evolocumab biosimilar research grade? Evolocumab (trade name Repatha) is a fully human monoclonal antibody that inhibits proprotein convertase subtilisin-kexin type 9 (PCSK9) and lowers low-density lipoprotein (LDL) cholesterol levels by approximately 60 % . The PCSK9 protein targets LDL receptors for degradation. Evolocumab binds to the circulating PCSK9 protein, inhibiting it from binding to the LDLR, in turn preventing PCSK9-mediated LDLR degradation and permitting the LDLR to recycle back to the liver cell surface. By inhibiting the binding of PCSK9 to LDLR, evolocumab increases the number of LDLRs available to clear LDL from the blood, thereby lowering LDL-C levels. Evolocumab biosimilar uses the same protein sequences as the therapeutic antibody evolocumab.

Purification: Protein A or G affinity column

Pureté: >95 % by reducing SDS-PAGE

niveau d'endotoxine: < 1 EU per 1 mg of the protein by the LAL method

Immunogène: Human PCSK9

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: > 3 mg/mL

Stock: 4 °C,-20 °C

Stockage commentaire: Short time 2 to 8°C as supplied. Long time -20°C to -70°C as supplied.

Détails sur PCSK9 (Evolocumab Biosimilar)

Antigène: PCSK9 (Evolocumab Biosimilar)

Autre désignation: Evolocumab Biosimilar

Classe de substances: Biosimilar