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Recombinant CEACAM5 (Tusamitamab Biosimilar) anticorps

Cet anticorps anti-CEACAM5 (Tusamitamab Biosimilar) est un anticorps Humanized Monoclonal détectant CEACAM5 (Tusamitamab Biosimilar) dans FACS et in vivo. Adapté pour Humain.
N° du produit ABIN7795147

Aperçu rapide pour Recombinant CEACAM5 (Tusamitamab Biosimilar) anticorps (ABIN7795147)

Antigène

CEACAM5 (Tusamitamab Biosimilar)

Type d'anticorp

Recombinant Antibody

Reactivité

Humain

Hôte

  • 2
  • 2
  • 1
Humanized

Clonalité

  • 3
  • 1
Monoclonal

Conjugué

  • 4
Cet anticorp CEACAM5 (Tusamitamab Biosimilar) est non-conjugé

Application

  • 3
  • 2
  • 1
  • 1
  • 1
  • 1
Flow Cytometry (FACS), In vivo Studies (in vivo)

Classe de qualité

Research Grade
  • Expression System

    Mammalian cells

    Fonction

    Tusamitamab Biosimilar, Human CEACAM5 Monoclonal Antibody

    Attributs du produit

    What is tusamitamab biosimilar research grade? Tusamitamab is a humanized IgG1-kappa monoclonal antibody targeting carcinoembryonic antigen-related cell adhesion molecule 5 (CEACAM5) which is overexpressed in tumors including non-small cell lung cancer (NSCLC) and pancreatic ductal adenocarcinoma (PDAC), and is an attractive target for therapies based on CAR-T cell or/and ADCs. Tusamitamab ravtansine (SAR408701) is an antibody-drug conjugate (ADC) combining a humanized monoclonal antibody and a potent cytotoxic maytansinoid derivative (DM4) inhibiting microtubule assembly. Tusamitamab biosimilar uses the same protein sequences as the therapeutic antibody tusamitamab.

    Purification

    Protein A or G affinity column

    Pureté

    >95 % by reducing SDS-PAGE

    niveau d'endotoxine

    < 1 EU per 1 mg of the protein by the LAL method

    Immunogène

    Human CEACAM5
  • Indications d'application

    Optimal working dilution should be determined by the investigator.

    Restrictions

    For Research Use only
  • Format

    Liquid

    Concentration

    > 3 mg/mL

    Stock

    4 °C,-20 °C

    Stockage commentaire

    Short time 2 to 8°C as supplied. Long time -20°C to -70°C as supplied.
  • Antigène

    CEACAM5 (Tusamitamab Biosimilar)

    Autre désignation

    Tusamitamab Biosimilar

    Classe de substances

    Biosimilar
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