Recombinant CD370 & CD47 anticorps

N° du produit ABIN7795543

Cet anticorps anti-CD370 & CD47 Bispecific Souris (Clone 10B4-A4) (ABIN7795543) détecte spécifiquement CD370 & CD47 dans ELISA, FACS, ICC, IHC, in vivo et WB. L’anticorps est réactif avec des échantillons de Souris.

Aperçu rapide pour Recombinant CD370 & CD47 anticorps (ABIN7795543)

Antigène: CD370 & CD47

Type d'anticorp: Recombinant Antibody

Reactivité: Souris

Hôte: Souris

Clonalité: Bispecific

Application: ELISA, Flow Cytometry (FACS), Immunocytochemistry (ICC), Immunohistochemistry (IHC), In vivo Studies (in vivo), Western Blotting (WB)

Classe de qualité: In vivo Grade

Clone: 10B4-A4

Détail du produit

Expression System: Mammalian cells

Fonction: In Vivo Grade Recombinant Anti-mouse CD370 / CD47 Bispecific Antibody, Mouse IgG2c LALAPG Kappa (Clone 10B4 / A4)

Attributs du produit: The rat anti-mouse CD370 (Clec9A or DNGR-1) monoclonal antibody 10B4 (rat IgG2a kappa) reacts with the mouse CD370 protein. CLEC9A (C-type lectin domain family 9 member A), a transmembrane glycoprotein with a single extracellular C-type lectin domain (CTLD), plays a role in the immune response. As an activation receptor, CLEC9A is expressed on myeloid lineage cells, helps process material from dead cells, recognizes filamentous actin when cell membranes are damaged, and helps present antigens to cytotoxic T cells. CLEC9A has an intracellular cytoplasmic tail with potential signaling motifs. CLEC9A is expressed on a subset of BDCA3+ dendritic cells and CD16- monocytes in humans, and is expressed on CD8+ conventional DCs and plasmacytoid DCs in mice. It is under investigation how the recombinant anti-mouse CD370 / CD47 bispecific antibodies (10B4 / A4) behave different from the individual monoclonal antibodies and their combination. Our recombinant anti-mouse CD370 / CD47 bispecific antibodies have a part (variable regions) or complete amino acid sequences of the rat anti-mouse CD370 antibody (hybridoma clone name or number: 10B4) and the rat anti-mouse CD47 antibody (hybridoma clone name or number: A4).

Purification: Protein A or G affinity column

Pureté: >95 % by reducing SDS-PAGE

niveau d'endotoxine: < 1 EU per 1 mg of the protein by the LAL method

Isotype: IgG2c, L234A, L235A, P329G, kappa

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: > 3 mg/mL

Stock: 4 °C,-20 °C

Stockage commentaire: Short time 2 to 8°C as supplied. Long time -20°C to -70°C as supplied.

Détail du antigène

Antigène: CD370 & CD47

Sub Type: Bispecific