TS (C-Term) anticorps

N° du produit ABIN7795593

L’anticorps anti-TS Polyclonal Lapin est utilisé pour la détection de TS dans des échantillons de Humain et Souris. Il a été validé pour WB, IHC et IP.

Aperçu rapide pour TS (C-Term) anticorps (ABIN7795593)

Antigène: TS

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Inconjugué

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunoprecipitation (IP)

Détail du produit

Épitope: C-Term

Fonction: Rabbit anti-TS Antibody Affinity Purified

Homologie: Bovine,Dog,Monkey,Pig,Rabbit,Rat

Purification: Antigen Affinity Purified

Immunogène: Between 263 and C-terminus

Isotype: IgG

Information d'application

Indications d'application: IHC,1500 - 12000. Epitope retrieval with citrate buffer pH 6.0 is recommended for FFPE tissue sections.,IP,6 μg/mg lysate,WB,12000 - 110,000

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1000 μg/mL

Buffer: Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C

Stockage commentaire: 2 - 8 °C

Date de péremption: 12 months

Détail du antigène

Antigène: TS

Sujet: Thymidylate synthetase (TS) catalyzes the methylation of deoxyuridylate to deoxythymidylate using 5,10-methylenetetrahydrofolate (methylene-THF) as a cofactor. This function maintains the dTMP (thymidine-5-prime monophosphate) pool critical for DNA replication and repair. The enzyme has been of interest as a target for cancer chemotherapeutic agents. TS is considered to be the primary site of action for 5-fluorouracil, 5-fluoro-2-prime-deoxyuridine, and some folate analogs [taken from NCBI Entrez Gene (Gene ID: 7298)].

ID gène: 7298

UniProt: P04818