Recombinant ARID1A anticorps (AA 750-800)
Aperçu rapide pour Recombinant ARID1A anticorps (AA 750-800) (ABIN7795677)
Antigène
Voir toutes ARID1A AnticorpsType d'anticorp
Reactivité
Hôte
Clonalité
Conjugué
Application
Clone
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Épitope
- AA 750-800
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Fonction
- Rabbit anti-ARID1A/BAF250 Recombinant Monoclonal Antibody [BLR279L]
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Purification
- Purified
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Immunogène
- Between 750 and 800
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Isotype
- IgG
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Indications d'application
- Flow-Cyt,Fixed in 4 % formaldehyde and permeabilized with 90 % methanol. 1 μL per 1 x 10^6 cells.,ICC,1100 to 1500. Epitope retrieval with citrate buffer pH 6.0 is recommended for FFPE cell sections.,IHC,1100 to 1500. Epitope retrieval with citrate buffer pH 6.0 is recommended for FFPE tissue sections.,IP,20 μL/mg lysate ,WB,11000 (3-8 % Tris-acetate gel recommended)
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 50 μg/mL
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Buffer
- Borate Buffered Saline (BBS) pH 8.2 with 0.1 % BSA and 0.09 % Sodium Azide
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Stock
- 4 °C
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Stockage commentaire
- 2 - 8 °C
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Date de péremption
- 12 months
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- ARID1A (AT Rich Interactive Domain 1A (SWI-Like) (ARID1A))
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Autre désignation
- ARID1A/BAF250
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Sujet
- The SWI/SNF-related, matrix-associated, actin-dependent regulators of chromatin (SMARC), also called BRG1-associated factors (BAFs), have been identified as components of the human SWI/SNF-like chromatin-remodeling protein complexes. SWI/SNF complexes possess ATPase and DNA helicase activity that promotes transcriptional activation of genes normally repressed by chromatin structure. ARID1A/BAF250 is a noncatalytic subunit that is a member of the ARID (AT-rich interactive domain-containing protein) family of DNA binding proteins. ARID1A/BAF250 has been shown to play a role in the tumor suppressor activity of the SWI/SNF complexes. ARID1A/BAF250 is required for differentiation-associated cell cycle arrest.
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ID gène
- 8289
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UniProt
- O14497
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Pathways
- Intracellular Steroid Hormone Receptor Signaling Pathway, Tube Formation
Antigène
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