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Apo-B100 anticorps (Agarose Beads)

L’anticorps Chèvre Polyclonal anti-Apo-B100 a été validé pour . Il convient pour détecter Apo-B100 dans des échantillons de Humain.
N° du produit ABIN7795845

Aperçu rapide pour Apo-B100 anticorps (Agarose Beads) (ABIN7795845)

Antigène

Voir toutes Apo-B100 Anticorps
Apo-B100 (Apoprotein B100 (Apo-B100))

Reactivité

  • 12
  • 3
  • 2
  • 2
Humain

Hôte

  • 9
  • 6
  • 4
Chèvre

Clonalité

  • 12
  • 7
Polyclonal

Conjugué

  • 14
  • 3
  • 1
  • 1
Cet anticorp Apo-B100 est non-conjugé

Application

Veuillez nous consulter SVP

Clone

G03
  • Épitope

    • 3
    • 1
    • 1
    • 1
    Agarose Beads

    Fonction

    Goat anti-Human ApoB-100 Antibody Agarose Immobilized

    Purification

    Purified

    Immunogène

    Human Apolipoprotein B100

    Isotype

    IgG
  • Restrictions

    For Research Use only
  • Format

    Liquid

    Concentration

    5 mg/mL

    Buffer

    75 mM PBS, 75 mM NaCl, 0.5 mM EDTA, 0.02 % Sodium azide, 0.1 mM PMSF, pH 7.3

    Agent conservateur

    Other preservative, PMSF, Sodium azide

    Précaution d'utilisation

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    Stock

    4 °C

    Stockage commentaire

    2 - 8 °C

    Date de péremption

    12 months
  • Antigène

    Apo-B100 (Apoprotein B100 (Apo-B100))

    Autre désignation

    ApoB-100

    Sujet

    ApoB exists in human plasma in two isoforms, ApoB-48 (Chen et al., 1987) and Apo B-100 (Wei et al., 1985, Yang et al., 1986a, 1989a,b, 1990, Chen et al., 1986, Yang et al., 1990, Yang and Pownall, 1992). Apo B-100 is the major physiological ligand for the LDL receptor. Apo B-100 is a large monomeric protein, containing 4536 amino acids (m.w. 515 kDa, Yang et al., 1986b). Apo B-100 is synthesized in the liver and is required for the assembly of VLDL. It is found in LDL and VLDL after the removal of the Apo A, E and C. Apo B-48 is present in chylomicrons and their remnants. It is essential for the intestinal absorption of dietary lipids. Apo B levels correlate with the risk of coronary disease. The Apo B protein is directly involved in the retention of LDL with the arterial wall (Olofsson and Boren, 2012). Apo B-48 is synthesized in the small intestine. It comprises approximately half of the N-terminal region of ApoB-100 and is the result of posttranscriptional mRNA editing by a stop codon in the intestine not found in the liver.

    ID gène

    338

    UniProt

    P04114
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