SSTR2 anticorps (AA 211-320)

N° du produit ABIN738216

Cet anticorps anti-SSTR2 est un anticorps Lapin Polyclonal détectant SSTR2 dans WB, ELISA et IHC (p). Adapté pour Humain et Souris. Ce Primary Antibody a été cité dans 2+ publications.

Aperçu rapide pour SSTR2 anticorps (AA 211-320) (ABIN738216)

Antigène: SSTR2 (Somatostatin Receptor 2 (SSTR2))

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp SSTR2 est non-conjugé

Application: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Détail du produit anti-SSTR2 anticorps

Épitope: AA 211-320

Réactivité croisée: Humain, Souris

Homologie: Rat,Dog,Cow,Pig,Horse,Chicken,Rabbit,Guinea Pig

Purification: Purified by Protein A.

Immunogène: KLH conjugated synthetic peptide derived from human SSTR2

Isotype: IgG

Information d'application

Indications d'application: WB 1:300-5000
ELISA 1:500-1000
IHC-P 1:200-400

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Date de péremption: 12 months

Références pour anticorps anti-SSTR2 (ABIN738216)

Sakai, Yonezawa, Yamawaki, Oyamada: "Alteration of somatostatin receptor 2 expression in canine mammary gland tumor." dans: The Journal of veterinary medical science / the Japanese Society of Veterinary Science, (2015) (PubMed).

Ruan, Yu, Xu, Zhang, Long, Shen: "Attenuation of stress-induced gastrointestinal motility disorder by gentiopicroside, from Gentiana macrophylla Pall." dans: Fitoterapia, Vol. 103, pp. 265-76, (2015) (PubMed).

Détails sur SSTR2

Antigène: SSTR2 (Somatostatin Receptor 2 (SSTR2))

Autre désignation: SSTR2/Somatostatin Receptor 2

Sujet:

Synonyms: Somatostatin receptor type 2, SS-2-R, SS2-R, SS2R, SRIF-1, SSTR2

Background: Receptor for somatostatin-14 and -28. This receptor is coupled via pertussis toxin sensitive G proteins to inhibition of adenylyl cyclase. In addition it stimulates phosphotyrosine phosphatase and PLC via pertussis toxin insensitive as well as sensitive G proteins. Inhibits calcium entry by suppressing voltage-dependent calcium channels. Acts as the functionally dominant somatostatin receptor in pancreatic alpha- and beta-cells where it mediates the inhibitory effect of somatostatin-14 on hormone secretion. Inhibits cell growth through enhancement of MAPK1 and MAPK2 phosphorylation and subsequent up-regulation of CDKN1B. Stimulates neuronal migration and axon outgrowth and may participate in neuron development and maturation during brain development. Mediates negative regulation of insulin receptor signaling through PTPN6. Inactivates SSTR3 receptor function following heterodimerization.

ID gène: 6752

UniProt: P30874