AGE anticorps

N° du produit ABIN738516

Détail du produit anti-AGE anticorps

Antigène: AGE (Advanced Glycation End Products (AGE))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp AGE est non-conjugé

Application: Western Blotting (WB), Flow Cytometry (FACS), ELISA, Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Specificité: Reacts with BSA-AGE.

Réactivité croisée: Humain, Souris, Rat

Purification: Purified by Protein A.

Immunogène: AGEs

Isotype: IgG

Information d'application

Indications d'application: WB 1:300-5000
ELISA 1:500-1000
FCM 1:20-100
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Date de péremption: 12 months

Références pour anticorps anti-AGE (ABIN738516)

Huang, Huang, Xie, Wang, Chen, Shen, Liu, Huang: "Sirt1 resists advanced glycation end products-induced expressions of fibronectin and TGF-β1 by activating the Nrf2/ARE pathway in glomerular mesangial cells." dans: Free radical biology & medicine, Vol. 65, pp. 528-40, (2013) (PubMed).

Ye, Yang, Kong, Han, Zhang, Zhang, Li, Liu, Shi, Xiong, Zhao: "Ginsenoside Rd attenuates early oxidative damage and sequential inflammatory response after transient focal ischemia in rats." dans: Neurochemistry international, Vol. 58, Issue 3, pp. 391-8, (2011) (PubMed).

Lu, Peng, Wang, Wang, Chen, Shen: "Effects of atorvastatin on progression of diabetic nephropathy and local RAGE and soluble RAGE expressions in rats." dans: Journal of Zhejiang University. Science. B, Vol. 12, Issue 8, pp. 652-9, (2011) (PubMed).

Détails sur AGE

Antigène: AGE (Advanced Glycation End Products (AGE))

Autre désignation: AGEs (AGE Produits)

Synonymes: anticorps RBP, anticorps RNBP, anticorps renin binding protein, anticorps RENBP

Classe de substances: Chemical

Sujet:

Synonyms: Advanced Glycation End products, Serum albumin, BSA, ALB

Background: Advanced Glycation End products (AGEs) are the result of a chain of chemical reactions after an initial glycation reaction. The intermediate products are known, variously, as Amadori, Schiff base and Maillard products, named after the researchers who first described them. (The literature is inconsistent in applying these terms. For example, Maillard reaction products are sometimes considered intermediates and sometimes end products.) Side products generated in intermediate steps may be oxidizing agents (such as hydrogen peroxide), or not (such as beta amyloid proteins). "Glycosylation" is sometimes used for "glycation" in the literature, usually as 'non-enzymatic glycosylation. The AGE-modified BSA was produced by reacting BSA with glycolaldehyde under sterile conditions followed by extensive dialysis and purification steps.

ID gène: 280717

UniProt: P02769