GM1123 anticorps (PE-Cy5)

N° du produit ABIN739587

Cet anticorps anti-GM1123 est un anticorps Lapin Polyclonal détectant GM1123 dans WB et FACS. Adapté pour Humain, Souris, Rat, Boeuf (Vache), Chien et Porc.

Aperçu rapide pour GM1123 anticorps (PE-Cy5) (ABIN739587)

Antigène: GM1123 (Predicted Gene 1123 (GM1123))

Reactivité: Humain, Souris, Rat, Boeuf (Vache), Chien, Porc

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp GM1123 est conjugé à/à la PE-Cy5

Application: Western Blotting (WB), Flow Cytometry (FACS)

Détail du produit anti-GM1123 anticorps (PE-Cy5)

Réactivité croisée: Humain, Souris, Rat

Homologie: Dog,Cow,Pig,Horse,Rabbit

Purification: Purified by Protein A.

Immunogène: KLH conjugated synthetic peptide derived from human Coxsackie Adenovirus Receptor

Isotype: IgG

Information d'application

Indications d'application: FCM(1:100-500)
Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Date de péremption: 12 months

Détails sur GM1123

Antigène: GM1123 (Predicted Gene 1123 (GM1123))

Autre désignation: Coxsackie Adenovirus Receptor

Sujet:

Synonyms: CAR, HCAR, CAR4/6, Coxsackievirus and adenovirus receptor, CVB3-binding protein, Coxsackievirus B-adenovirus receptor, HCVADR, CXADR

Background: Component of the epithelial apical junction complex that may function as an homophilic cell adhesion molecule and is essential for tight junction integrity. Also involved in transepithelial migration of leukocytes through adhesive interactions with AMICA1/JAML a transmembrane protein of the plasma membrane of leukocytes. The interaction between both receptors also mediates the activation of gamma-delta T-cells, a subpopulation of T-cells residing in epithelia and involved in tissue homeostasis and repair. Upon epithelial CXADR-binding, AMICA1 induces downstream cell signaling events in gamma-delta T-cells through PI3-kinase and MAP kinases. It results in proliferation and production of cytokines and growth factors by T-cells that in turn stimulate epithelial tissues repair.

Poids moléculaire: 40kDa

ID gène: 1525

UniProt: P78310