C10orf2 anticorps (AA 39-635)

N° du produit ABIN7825314

Cet anticorps Lapin Polyclonal détecte spécifiquement C10orf2 dans WB et ELISA. Il présente une réactivité avec des échantillons de Humain, Souris et Rat.

Aperçu rapide pour C10orf2 anticorps (AA 39-635) (ABIN7825314)

Antigène: C10orf2 (C10ORF2) (Chromosome 10 Open Reading Frame 2 (C10ORF2))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp C10orf2 est non-conjugé

Application: Western Blotting (WB), ELISA

Détail du produit anti-C10orf2 anticorps

Épitope: AA 39-635

Fonction: Anti-Twinkle/TWNK Antibody

Réactivité croisée (Details): No cross-reactivity with other proteins

Homologie: Human Twinkle,TWNK shares 87.8% amino acid (aa) sequence identity with mouse Twinkle,TWNK.

Attributs du produit: Anti-Twinkle/TWNK Antibody. Tested in WB, ELISA applications. This antibody reacts with Human, Mouse, Rat.

Purification: Immunogen affinity purified.

Immunogène: E.coli-derived human Twinkle/TWNK recombinant protein (Position: R39-K635). Human Twinkle/TWNK shares 87.8% amino acid (aa) sequence identity with mouse Twinkle/TWNK.

Isotype: IgG

Information d'application

Indications d'application: Western blot, 0.25-0.5 μg/mL, Human, Mouse, Rat ELISA, 0.1-0.5 μg/mL

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Concentration: 500 μg/mL

Buffer: Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.

Stock: 4 °C,-20 °C

Stockage commentaire: At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.

Date de péremption: 12 months

Détails sur C10orf2

Antigène: C10orf2 (C10ORF2) (Chromosome 10 Open Reading Frame 2 (C10ORF2))

Autre désignation: TWNK

Sujet:

Background: This gene encodes a hexameric DNA helicase which unwinds short stretches of double-stranded DNA in the 5' to 3' direction and, along with mitochondrial single-stranded DNA binding protein and mtDNA polymerase gamma, is thought to play a key role in mtDNA replication. The protein localizes to the mitochondrial matrix and mitochondrial nucleoids. Mutations in this gene cause infantile onset spinocerebellar ataxia (IOSCA) and progressive external ophthalmoplegia (PEO) and are also associated with several mitochondrial depletion syndromes. Alternative splicing results in multiple transcript variants encoding distinct isoforms.

Gene Full Name: twinkle mtDNA helicase

Poids moléculaire: 70 kDa

ID gène: 56652

UniProt: Q96RR1