Recombinant ABCE1 anticorps

N° du produit ABIN7828031

L’anticorps anti-ABCE1 Monoclonal Lapin est utilisé pour la détection de ABCE1 dans des échantillons de Humain et Souris. Il a été validé pour WB et IF.

Aperçu rapide pour Recombinant ABCE1 anticorps (ABIN7828031)

Antigène: ABCE1 (ATP-Binding Cassette, Sub-Family E (OABP), Member 1 (ABCE1))

Type d'anticorp: Recombinant Antibody

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Monoclonal

Conjugué: Cet anticorp ABCE1 est non-conjugé

Application: Western Blotting (WB), Immunofluorescence (IF)

Clone: A119

Détail du produit anti-ABCE1 anticorps

Fonction: Recombinant ABCE1 Monoclonal Antibody

Purification: Protein A purified

Immunogène: Recombinant human ABCE1 fragment

Isotype: IgG, kappa

Information d'application

Indications d'application: WB 1:500-1:1000,IF 1:50

Restrictions: For Research Use only

Stockage

Concentration: 1 mg/mL

Buffer: PBS, 50 % glycerol, 0.05 % Proclin 300, 0.05 % protein protectant.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

Date de péremption: 12 months

Détails sur ABCE1

Antigène: ABCE1 (ATP-Binding Cassette, Sub-Family E (OABP), Member 1 (ABCE1))

Autre désignation: ABCE1

Sujet: ABC,ABCE,RNASEL,OK/SW-cl,ABCE1,ABC38,OABP,RLI,RLI1,RNASEL1,RNASELI,RNS4I,OK/SW-cl.40,2' 5' oligoadenylate binding protein,2'5' oligoadenylate binding protein,2''-5''-oligoadenylate-binding protein,ABC 38,ABCE 1,ATP binding cassette sub family E (OABP) member 1,ATP binding cassette sub family E member 1,ATP-binding cassette sub-family E member 1,HuHP 68,HuHP68,Ribonuclease 4 inhibitor,Ribonuclease L (2' 5' oligoisoadenylate synthetase dependent) inhibitor,Ribonuclease L (2'5' oligoisoadenylate synthetase dependent) inhibitor,Ribonuclease L inhibitor,RNase L inhibitor,RNS 4I,Cotranslational quality control factor involved in the No-Go Decay (NGD) pathway. Together with PELO and HBS1L, is required for 48S complex formation from 80S ribosomes and dissociation of vacant 80S ribosomes. Together with PELO and HBS1L, recognizes stalled ribosomes and promotes dissociation of elongation complexes assembled on non-stop mRNAs, this triggers endonucleolytic cleavage of the mRNA, a mechanism to release non-functional ribosomes and to degrade damaged mRNAs as part of the No-Go Decay (NGD) pathway. Plays a role in the regulation of mRNA turnover. Plays a role in quality control of translation of mitochondrial outer membrane-localized mRNA. As part of the PINK1-regulated signaling, ubiquitinated by CNOT4 upon mitochondria damage, this modification generates polyubiquitin signals that recruit autophagy receptors to the mitochondrial outer membrane and initiate mitophagy. RNASEL-specific protein inhibitor which antagonizes the binding of 2-5A (5'-phosphorylated 2',5'-linked oligoadenylates) to RNASEL. Negative regulator of the anti-viral effect of the interferon-regulated 2-5A/RNASEL pathway. Cat.No. Product Name Clone No. IF:{{item.impact}} Journal:{{item.journal}} ({{item.year}}) DOI:{{item.doi}} Reactivity:{{item.species}} Sample Type:{{item.sample_type}} Previous {{ page }} Next Q{{(FAQpage.currentPage - 1)*pageSize+index+1}}:{{item.name}} Previous {{ page }} Next [

Poids moléculaire:

Calculated MW: 34 kDa

Observed MW: 45 kDa The actual band is not consistent with the expectation.

UniProt: P61221