Recombinant BCL6 anticorps

N° du produit ABIN7828037

L’anticorps anti-BCL6 Monoclonal Lapin est utilisé pour la détection de BCL6 dans des échantillons de Humain. Il a été validé pour IHC et WB.

Aperçu rapide pour Recombinant BCL6 anticorps (ABIN7828037)

Antigène: BCL6 (B-Cell CLL/lymphoma 6 (BCL6))

Type d'anticorp: Recombinant Antibody

Reactivité: Humain

Hôte: Lapin

Clonalité: Monoclonal

Conjugué: Cet anticorp BCL6 est non-conjugé

Application: Immunohistochemistry (IHC), Western Blotting (WB)

Clone: A139

Détail du produit anti-BCL6 anticorps

Fonction: Recombinant BCL6 Monoclonal Antibody

Purification: Protein A purified

Immunogène: Recombinant human BCL6 fragment

Isotype: IgG, kappa

Information d'application

Indications d'application: WB 1:1000-1:5000,IHC 1:100-1:500

Restrictions: For Research Use only

Stockage

Concentration: 1 mg/mL

Buffer: PBS, 50 % glycerol, 0.05 % Proclin 300, 0.05 % protein protectant.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

Date de péremption: 12 months

Détails sur BCL6

Antigène: BCL6 (B-Cell CLL/lymphoma 6 (BCL6))

Autre désignation: BCL6

Sujet: ZNF,LAZ,ZBTB,BCL,BCL6,BCL5,BCL6A,LAZ3,ZBTB27,ZNF51,Transcriptional repressor mainly required for germinal center (GC) formation and antibody affinity maturation which has different mechanisms of action specific to the lineage and biological functions. In response to genotoxic stress, controls cell cycle arrest in GC B-cells in both p53/TP53-dependedent and -independent manners. Besides, also controls neurogenesis through the alteration of the composition of NOTCH-dependent transcriptional complexes at selective NOTCH targets, such as HES5, including the recruitment of the deacetylase SIRT1 and resulting in an epigenetic silencing leading to neuronal differentiation. Cat.No. Product Name Clone No. IF:{{item.impact}} Journal:{{item.journal}} ({{item.year}}) DOI:{{item.doi}} Reactivity:{{item.species}} Sample Type:{{item.sample_type}} Previous {{ page }} Next Q{{(FAQpage.currentPage - 1)*pageSize+index+1}}:{{item.name}} Previous {{ page }} Next [

Poids moléculaire:

Calculated MW: 79 kDa

Observed MW: 78 kDa The actual band is not consistent with the expectation.

UniProt: P41182

Pathways: Chromatin Binding, Regulation of Leukocyte Mediated Immunity, Production of Molecular Mediator of Immune Response, Protein targeting to Nucleus