Recombinant CPT1B anticorps
Aperçu rapide pour Recombinant CPT1B anticorps (ABIN7828065)
Antigène
Voir toutes CPT1B AnticorpsType d'anticorp
Reactivité
Hôte
Clonalité
Conjugué
Application
Clone
-
-
Fonction
- Recombinant CPT1B Monoclonal Antibody
-
Purification
- Protein A purified
-
Immunogène
- Recombinant human CPT1B fragment
-
Isotype
- IgG, kappa
-
-
-
-
Indications d'application
- WB 1:1000-1:5000,IHC 1:50
-
Restrictions
- For Research Use only
-
-
-
Concentration
- 1 mg/mL
-
Buffer
- PBS, 50 % glycerol, 0.05 % Proclin 300, 0.05 % protein protectant.
-
Agent conservateur
- ProClin
-
Précaution d'utilisation
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
Stock
- -20 °C
-
Stockage commentaire
- Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
-
Date de péremption
- 12 months
-
-
- CPT1B (Carnitine Palmitoyltransferase 1B (Muscle) (CPT1B))
-
Autre désignation
- CPT1B
-
Sujet
- KIAA,KIAA1670,CPT1B,CPT I,CPT1-M,CPTI-M,Carnitine palmitoyltransferase-1 (CPT1), localized to the mitochondrial outer membrane, translocates fatty acids across the mitochondrial membranes and catalyzes the rate-limiting step of β-oxidation. There are three isoforms of this enzyme: CPT1A (liver), CPT1B (muscle), and CPT1C (brain). Deficiency of CPT1A results in an autosomal recessive mitochondrial fatty acid oxidation disorder. Studies have shown that physiological high blood glucose and insulin levels inhibit CPT1B activity in human muscle and therefore divert long-chain fatty acids toward storage in human muscle as triglycerides. Furthermore, mice deficient in CPT1C show less food intake and reduced body weight. These findings suggest that CPT1 may play a role in metabolic syndromes. Cat.No. Product Name Clone No. IF:{{item.impact}} Journal:{{item.journal}} ({{item.year}}) DOI:{{item.doi}} Reactivity:{{item.species}} Sample Type:{{item.sample_type}} Previous {{ page }} Next Q{{(FAQpage.currentPage - 1)*pageSize+index+1}}:{{item.name}} Previous {{ page }} Next [
-
Poids moléculaire
-
Calculated MW: 87 kDa
Observed MW: 87 kDa
-
UniProt
- Q92523
-
Pathways
- AMPK Signaling, Monocarboxylic Acid Catabolic Process
Antigène
-