Recombinant Caveolin-1 anticorps (pTyr14)

N° du produit ABIN7828072

Cet anticorps Lapin Monoclonal détecte spécifiquement Caveolin-1 dans WB. Il présente une réactivité avec des échantillons de Humain.

Aperçu rapide pour Recombinant Caveolin-1 anticorps (pTyr14) (ABIN7828072)

Antigène: Caveolin-1 (CAV1) (Caveolin 1, Caveolae Protein, 22kDa (CAV1))

Type d'anticorp: Recombinant Antibody

Reactivité: Humain

Hôte: Lapin

Clonalité: Monoclonal

Conjugué: Cet anticorp Caveolin-1 est non-conjugé

Application: Western Blotting (WB)

Clone: A813

Détail du produit anti-Caveolin-1 anticorps

Épitope: pTyr14

Fonction: Recombinant Phospho-Caveolin-1 (Tyr14) Monoclonal Antibody

Purification: Protein A purified

Immunogène: phosphorylated human Caveolin-1 (Tyr14) peptide

Isotype: IgG, kappa

Information d'application

Indications d'application: WB 1:500-1:1000

Restrictions: For Research Use only

Stockage

Concentration: 1 mg/mL

Buffer: PBS, 50 % glycerol, 0.05 % Proclin 300, 0.05 % protein protectant.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

Date de péremption: 12 months

Détails sur Caveolin-1

Antigène: Caveolin-1 (CAV1) (Caveolin 1, Caveolae Protein, 22kDa (CAV1))

Autre désignation: Caveolin-1

Sujet: PPH,CGL,BSCL,MSTP,cell growth-inhibiting protein,OTTHUMP,VIP,BSCL3,CGL3,LCCNS,MSTP085,PPH3,VIP21,CAV1,22 kD,caveolae protein,caveolin 1 alpha isoform,caveolin 1 beta isoform,Caveolin 1 caveolae protein 22 kDa,Caveolin1,Caveolin-1,cell growth-inhibiting protein 32,OTTHUMP00000025031,VIP 21,CAV,Caveolins are the principal structural components of the cholesterol/sphingolipid-enriched plasma membrane microdomain caveolae. Three members of the caveolin family (caveolin-1, -2, and -3) have been identified with different tissue distributions. Caveolins form hetero- and homo-oligomers that interact with cholesterol and other lipids. Caveolins are involved in diverse biological functions, including vesicular trafficking, cholesterol homeostasis, cell adhesion, and apoptosis, and are also implicated in neurodegenerative disease. Caveolins interact with multiple signaling molecules, such as Gα subunit, tyrosine kinase receptors, PKCs, Src family tyrosine kinases, and eNOS. It is believed that caveolins serve as scaffolding proteins for the integration of signal transduction. Phosphorylation at Tyr14 is essential for caveolin association with SH2 or PTB domain-containing adaptor proteins, such as GRB7. Phosphorylation at Ser80 regulates caveolin binding to the ER membrane and entry into the secretory pathway. Cat.No. Product Name Clone No. IF:{{item.impact}} Journal:{{item.journal}} ({{item.year}}) DOI:{{item.doi}} Reactivity:{{item.species}} Sample Type:{{item.sample_type}} Previous {{ page }} Next Q{{(FAQpage.currentPage - 1)*pageSize+index+1}}:{{item.name}} Previous {{ page }} Next [

Poids moléculaire:

Calculated MW: 20 kDa

Observed MW: 22 kDa The actual band is not consistent with the expectation.

UniProt: Q03135

Pathways: Maintenance of Protein Location, Signaling Events mediated by VEGFR1 and VEGFR2, Negative Regulation of Transporter Activity, VEGFR1 Specific Signals