Recombinant CD276 anticorps

N° du produit ABIN7828078

Cet anticorps Lapin Monoclonal détecte spécifiquement CD276 dans WB, FACS, IHC, IP et IF. Il présente une réactivité avec des échantillons de Humain et Souris.

Aperçu rapide pour Recombinant CD276 anticorps (ABIN7828078)

Antigène: CD276

Type d'anticorp: Recombinant Antibody

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Monoclonal

Conjugué: Cet anticorp CD276 est non-conjugé

Application: Western Blotting (WB), Flow Cytometry (FACS), Immunohistochemistry (IHC), Immunoprecipitation (IP), Immunofluorescence (IF)

Clone: A137

Détail du produit anti-CD276 anticorps

Fonction: Recombinant B7-H3/CD276 Monoclonal Antibody

Purification: Protein A purified

Immunogène: Recombinant human B7-H3/CD276 fragment

Isotype: IgG, kappa

Information d'application

Indications d'application: WB 1:500-1:2000,IHC 1:200-1:1000,IF 1:50,FCM 1:50-1:100,IP 1:25-1:100

Restrictions: For Research Use only

Stockage

Concentration: 1 mg/mL

Buffer: PBS, 50 % glycerol, 0.05 % Proclin 300, 0.05 % protein protectant.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

Date de péremption: 12 months

Détails sur CD276

Antigène: CD276

Autre désignation: B7-H3/CD276

Sujet: B7H,UNQ,PRO,B7-H,B7RP,B7 homolog,B7H34Ig-B7-H,PSEC,4Ig-B7-H,CD276,4Ig-B7-H3,B7-H3,B7H3,B7RP-2,B7 homolog 3,B7H34Ig-B7-H3,CD276 antigen,CD276 Molecule,Costimulatory molecule,PSEC0249,UNQ309,PRO352,B7RP-2,4Ig-B7-H3,B7H3,B7-H3,CD276 antigen,May participate in the regulation of T-cell-mediated immune response. May play a protective role in tumor cells by inhibiting natural-killer mediated cell lysis as well as a role of marker for detection of neuroblastoma cells. May be involved in the development of acute and chronic transplant rejection and in the regulation of lymphocytic activity at mucosal surfaces. Could also play a key role in providing the placenta and fetus with a suitable immunological environment throughout pregnancy. Both isoform 1 and isoform 2 appear to be redundant in their ability to modulate CD4 T-cell responses. Isoform 2 is shown to enhance the induction of cytotoxic T-cells and selectively stimulates interferon gamma production in the presence of T-cell receptor signaling. Cat.No. Product Name Clone No. IF:{{item.impact}} Journal:{{item.journal}} ({{item.year}}) DOI:{{item.doi}} Reactivity:{{item.species}} Sample Type:{{item.sample_type}} Previous {{ page }} Next Q{{(FAQpage.currentPage - 1)*pageSize+index+1}}:{{item.name}} Previous {{ page }} Next [

Poids moléculaire:

Calculated MW: 57 kDa

Observed MW: 110 kDa The actual band is not consistent with the expectation.

UniProt: Q5ZPR3

Pathways: Cancer Immune Checkpoints