Recombinant Claudin 1 anticorps

N° du produit ABIN7828115

L’anticorps anti-Claudin 1 Monoclonal Lapin est utilisé pour la détection de Claudin 1 dans des échantillons de Humain. Il a été validé pour WB, IHC et IP.

Aperçu rapide pour Recombinant Claudin 1 anticorps (ABIN7828115)

Antigène: Claudin 1 (CLDN1)

Type d'anticorp: Recombinant Antibody

Reactivité: Humain

Hôte: Lapin

Clonalité: Monoclonal

Conjugué: Cet anticorp Claudin 1 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunoprecipitation (IP)

Clone: A187

Détail du produit anti-Claudin 1 anticorps

Fonction: Recombinant Claudin-1 Monoclonal Antibody

Purification: Protein A purified

Immunogène: Recombinant human Claudin-1 fragment

Isotype: IgG, kappa

Information d'application

Indications d'application: WB 1:500-1:2000,IHC 1:200-1:1000,IP 1:50-1:100

Restrictions: For Research Use only

Stockage

Concentration: 1 mg/mL

Buffer: PBS, 50 % glycerol, 0.05 % Proclin 300, 0.05 % protein protectant.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

Date de péremption: 12 months

Détails sur Claudin 1

Antigène: Claudin 1 (CLDN1)

Autre désignation: Claudin-1

Sujet: UNQ,PRO,CLD,CLDN1,CLD1,ILVASC,SEMP1,claudin-1,Claudin1,CLD 1,CLDN 1,SEMP 1,Senescence associated epithelial membrane protein,Senescence associated epithelial membrane protein 1,Senescence-associated epithelial membrane protein,UNQ481,PRO944,claudin-1,CLD1,ILVASC,SEMP1,Claudins function as major constituents of the tight junction complexes that regulate the permeability of epithelia. While some claudin family members play essential roles in the formation of impermeable barriers, others mediate the permeability to ions and small molecules. Often, several claudin family members are coexpressed and interact with each other, and this determines the overall permeability. CLDN1 is required to prevent the paracellular diffusion of small molecules through tight junctions in the epidermis and is required for the normal barrier function of the skin. Required for normal water homeostasis and to prevent excessive water loss through the skin, probably via an indirect effect on the expression levels of other proteins, since CLDN1 itself seems to be dispensable for water barrier formation in keratinocyte tight junctions. Cat.No. Product Name Clone No. IF:{{item.impact}} Journal:{{item.journal}} ({{item.year}}) DOI:{{item.doi}} Reactivity:{{item.species}} Sample Type:{{item.sample_type}} Previous {{ page }} Next Q{{(FAQpage.currentPage - 1)*pageSize+index+1}}:{{item.name}} Previous {{ page }} Next [

Poids moléculaire:

Calculated MW: 22 kDa

Observed MW: 18 kDa The actual band is not consistent with the expectation.

UniProt: O95832

Pathways: Cell-Cell Junction Organization, Hepatitis C