Recombinant EGR2 anticorps

N° du produit ABIN7828167

Cet anticorps anti-EGR2 Monoclonal Lapin (Clone A776) (ABIN7828167) détecte spécifiquement EGR2 dans WB. L’anticorps est réactif avec des échantillons de Humain, Souris et Rat.

Aperçu rapide pour Recombinant EGR2 anticorps (ABIN7828167)

Antigène: EGR2 (Early Growth Response 2 (EGR2))

Type d'anticorp: Recombinant Antibody

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Monoclonal

Conjugué: Cet anticorp EGR2 est non-conjugé

Application: Western Blotting (WB)

Clone: A776

Détail du produit anti-EGR2 anticorps

Fonction: Recombinant EGR2 Monoclonal Antibody

Purification: Protein A purified

Isotype: IgG, kappa

Information d'application

Indications d'application: WB 1:1000

Restrictions: For Research Use only

Stockage

Concentration: 1 mg/mL

Buffer: PBS, 50 % glycerol, 0.05 % Proclin 300, 0.05 % protein protectant.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

Date de péremption: 12 months

Détails sur EGR2

Antigène: EGR2 (Early Growth Response 2 (EGR2))

Autre désignation: EGR2

Sujet: EGR,KROX,EGR2,AT591,CMT1D,CMT4E,KROX20,DKFZp686J1957,Drosophila,E3 SUMO-protein ligase EGR2,early growth response 2,Early growth response protein 2,EGR-2,FLJ14547,homolog (early growth response-2),KROX 20 Drosophila homolog,Krox 20 homolog Drosophila,KROX-20,Krox20 protein,Zinc finger protein Krox-20,EGR2 is also named as KROX20, belongs to the EGR C2H2-type zinc-finger protein family. As a zinc finger transcription factor, it is observed in both the somata and dendrites of central neurons. EGR2 plays an important role in the transient formation of hindbrain developmental compartments or rhombomeres and is also an important factor in peripheral myelination, maintenance of synaptic plasticity and long-term potentiation. EGR2 expression is induced downstream of TCR signaling in NKT precursors and EGR2 is directly connected with the key molecular checkpoints defining NKT lineage commitment and stage progression, suggesting that EGR2 not only induces the early lineage-defining transcription factor PLZF, but also controls the downstream expression of the IL-2Rβ chain. EGR2 is regulated by both soluble and membrane-bound neuregulins and its concentration is partially modulated by calcium-dependent events. EGR2/Krox20 is also required for induction of Pmp22, and is nuclear-localized. Cat.No. Product Name Clone No. IF:{{item.impact}} Journal:{{item.journal}} ({{item.year}}) DOI:{{item.doi}} Reactivity:{{item.species}} Sample Type:{{item.sample_type}} Previous {{ page }} Next Q{{(FAQpage.currentPage - 1)*pageSize+index+1}}:{{item.name}} Previous {{ page }} Next [

Poids moléculaire:

Calculated MW: 50 kDa

Observed MW: 55 kDa The actual band is not consistent with the expectation.

UniProt: P11161