Recombinant CD39 anticorps

N° du produit ABIN7828168

Cet anticorps Lapin Monoclonal détecte spécifiquement CD39 dans WB. Il présente une réactivité avec des échantillons de Humain et Souris.

Aperçu rapide pour Recombinant CD39 anticorps (ABIN7828168)

Antigène: CD39 (ENTPD1) (Ectonucleoside Triphosphate diphosphohydrolase 1 (ENTPD1))

Type d'anticorp: Recombinant Antibody

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Monoclonal

Conjugué: Cet anticorp CD39 est non-conjugé

Application: Western Blotting (WB)

Clone: A701

Détail du produit anti-CD39 anticorps

Fonction: Recombinant CD39 Monoclonal Antibody

Purification: Protein A purified

Immunogène: Recombinant fragment

Isotype: IgG, kappa

Information d'application

Indications d'application: WB 1:1000-1:2000

Restrictions: For Research Use only

Stockage

Concentration: 1 mg/mL

Buffer: PBS, 50 % glycerol, 0.05 % Proclin 300, 0.05 % protein protectant.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

Date de péremption: 12 months

Détails sur CD39

Antigène: CD39 (ENTPD1) (Ectonucleoside Triphosphate diphosphohydrolase 1 (ENTPD1))

Autre désignation: CD39

Sujet: SPG,Ecto-ATP diphosphohydrolase,Ectonucleoside triphosphate diphosphohydrolase,ENTPD,ENTPD1,ATPDase,CD39,NTPDase-1,SPG64,CD 39,NTPDase1,Ecto-apyrase,Ectonucleoside triphosphate diphosphohydrolase 1,NTPDase 1,Ecto-ATP diphosphohydrolase 1,Lymphoid cell activation antigen,NTPDase-1,CD39 antigen,DKFZp686D194,DKFZp686I093,Ecto apyrase,Ecto ATP diphosphohydrolase,Ecto-ATPase 1,Ecto-ATPDase 1,ENTP1,ENTPD 1,FLJ40921,FLJ40959,CD39,also known as ectonucleoside triphosphate diphosphohydrolase 1 (NTPDase 1), is a multi-pass membrane ectoenzyme that metabolizes adenosine-5'-triphosphate (ATP) to regulate purinergic signaling. Purinergic signaling by extracellular ATP and its metabolites regulate many biological processes, including vascular tone, digestion, neuronal function, and inflammation in both normal and diseased states. CD39 is expressed in endothelial cells in the vasculature to regulate local platelet purinergic signaling via metabolism of ATP to adenosine. Accordingly, CD39 regulates platelet activation aggregation and contributes to the antithrombotic properties of endothelial cells. ATP and its metabolites also finely modulate the activity of T cells and macrophages. Immunomodulation is regulated, in part, by the availability of extracellular ATP and adenosine, suggesting that CD39 may play an immunosuppressive role in the tumor microenvironment. Cat.No. Product Name Clone No. IF:{{item.impact}} Journal:{{item.journal}} ({{item.year}}) DOI:{{item.doi}} Reactivity:{{item.species}} Sample Type:{{item.sample_type}} Previous {{ page }} Next Q{{(FAQpage.currentPage - 1)*pageSize+index+1}}:{{item.name}} Previous {{ page }} Next [

Poids moléculaire:

Calculated MW: 58 kDa

Observed MW: 78 kDa The actual band is not consistent with the expectation.

UniProt: P49961