Recombinant ELANE anticorps

N° du produit ABIN7828171

Cet anticorps Lapin Monoclonal détecte spécifiquement ELANE dans WB. Il présente une réactivité avec des échantillons de Humain.

Aperçu rapide pour Recombinant ELANE anticorps (ABIN7828171)

Antigène: ELANE (Elastase, Neutrophil Expressed (ELANE))

Type d'anticorp: Recombinant Antibody

Reactivité: Humain

Hôte: Lapin

Clonalité: Monoclonal

Conjugué: Cet anticorp ELANE est non-conjugé

Application: Western Blotting (WB)

Clone: A585

Détail du produit anti-ELANE anticorps

Fonction: Recombinant Neutrophil Elastase Monoclonal Antibody

Purification: Protein A purified

Immunogène: Recombinant human Neutrophil Elastase fragment

Isotype: IgG, kappa

Information d'application

Indications d'application: WB 1:1000-1:5000

Restrictions: For Research Use only

Stockage

Concentration: 1 mg/mL

Buffer: PBS, 50 % glycerol, 0.05 % Proclin 300, 0.05 % protein protectant.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

Date de péremption: 12 months

Détails sur ELANE

Antigène: ELANE (Elastase, Neutrophil Expressed (ELANE))

Autre désignation: Neutrophil Elastase

Sujet: SCN,ELA,Elastase,ELANE,ELA2,GE,HLE,HNE,NE,PMN-E,SCN1,Elastase-2,Medullasin,Neutrophil elastase,Bone marrow serine protease,Human leukocyte elastase,PMN elastase,Elastase 2,Elastase 2 neutrophil,Elastase neutrophil expressed,ELNE,Granulocyte derived elastase,Leukocyte elastase,Neutrophil expressed,PMN E,Polymorphonuclear elastase,Neutrophil Elastase is hematopoietic serine protease that belongs to the chymotrypsin superfamily and plays a critical role in the innate immune function of mature neutrophils and monocytes. Neutrophil elastase is actively synthesized as an inactive zymogen in myelocytic precursor cells of the bone marrow, which then undergoes activation by limited proteolysis and sorting to primary (azurophil) storage granules of mature neutrophil granulocytes for regulated release. Research studies have shown that neutrophils play a significant role in mediating the inflammatory response through the release of neutrophil elastase, which activates pro-inflammatory cytokines and degrades components of the extracellular matrix and Gram-negative bacteria. Mutations in the gene encoding neutrophil elastase, ELA2, have been implicated in hematological diseases such as cyclic and severe congenital neutropenia, which is characterized by defects in promyelocyte maturation. Cat.No. Product Name Clone No. IF:{{item.impact}} Journal:{{item.journal}} ({{item.year}}) DOI:{{item.doi}} Reactivity:{{item.species}} Sample Type:{{item.sample_type}} Previous {{ page }} Next Q{{(FAQpage.currentPage - 1)*pageSize+index+1}}:{{item.name}} Previous {{ page }} Next [

Poids moléculaire:

Calculated MW: 29 kDa

Observed MW: 29 kDa

UniProt: P08246