Recombinant EIF4G1 anticorps

N° du produit ABIN7828190

L’anticorps anti-EIF4G1 Monoclonal Lapin est utilisé pour la détection de EIF4G1 dans des échantillons de Humain et Souris. Il a été validé pour WB et IHC.

Aperçu rapide pour Recombinant EIF4G1 anticorps (ABIN7828190)

Antigène: EIF4G1 (Eukaryotic Translation Initiation Factor 4 Gamma, 1 (EIF4G1))

Type d'anticorp: Recombinant Antibody

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Monoclonal

Conjugué: Cet anticorp EIF4G1 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Clone: A669

Détail du produit anti-EIF4G1 anticorps

Fonction: Recombinant eIF4G1 Monoclonal Antibody

Purification: Protein A purified

Immunogène: Recombinant human eIF4G1 fragment

Isotype: IgG, kappa

Information d'application

Indications d'application: WB 1:1000,IHC 1:500-1:1000

Restrictions: For Research Use only

Stockage

Concentration: 1 mg/mL

Buffer: PBS, 50 % glycerol, 0.05 % Proclin 300, 0.05 % protein protectant.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

Date de péremption: 12 months

Détails sur EIF4G1

Antigène: EIF4G1 (Eukaryotic Translation Initiation Factor 4 Gamma, 1 (EIF4G1))

Autre désignation: eIF4G1

Sujet: PARK,DKFZp686A,eIF 4 gamma,eIF-4-gamma,Eukaryotic translation initiation factor 4 gamma,IF4G,EIF4G1,EIF-4G1,EIF4F,EIF4G,EIF4GI,P220,PARK18,DKFZp686A1451,eIF 4 gamma 1,eIF 4G 1,eIF 4G1,EIF4 gamma,eIF-4G 1,eIF-4-gamma 1,Eukaryotic translation initiation factor 4 gamma 1,IF4G1,The initiation of translation is an important biological event and a variety of factors contribute to this process. Members of the eIF4 translation initiation factor family bind to the 5' m7GTP mRNA cap and unwind the mRNA secondary structure. The amino-terminal portion of eIF4G physically associates with eIF4E to stimulate the binding of eIF4E to the mRNA cap structure. eIF4G also interacts with eIF3 and eIF4A and serves as an adaptor molecule in the eIF4 complex. Moreover, eIF4G plays a role in internal ribosomal entry site (IRES)-mediated initiation of translation. The eIF4G family includes eIF4G1 (eIF4GI), eIF4G2 (p97, DAP5 or NAT1), and eIF4G3 (eIF4GII). These factors share a homologous sequence that provides for interaction with initiation factors eIF3 and eIF4A. Both eIF4G1 and eIF4G3 are involved in cap-dependent translation, while eIF4G2 plays a role in IRES-mediated translation of some genes during cell stress. Cat.No. Product Name Clone No. IF:{{item.impact}} Journal:{{item.journal}} ({{item.year}}) DOI:{{item.doi}} Reactivity:{{item.species}} Sample Type:{{item.sample_type}} Previous {{ page }} Next Q{{(FAQpage.currentPage - 1)*pageSize+index+1}}:{{item.name}} Previous {{ page }} Next [

Poids moléculaire:

Calculated MW: 175 kDa

Observed MW: 250 kDa The actual band is not consistent with the expectation.

UniProt: Q04637