Recombinant FGL1 anticorps

N° du produit ABIN7828204

Cet anticorps Lapin Monoclonal détecte spécifiquement FGL1 dans WB et IHC. Il présente une réactivité avec des échantillons de Humain.

Aperçu rapide pour Recombinant FGL1 anticorps (ABIN7828204)

Antigène: FGL1 (Fibrinogen-Like 1 (FGL1))

Type d'anticorp: Recombinant Antibody

Reactivité: Humain

Hôte: Lapin

Clonalité: Monoclonal

Conjugué: Cet anticorp FGL1 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Clone: A637

Détail du produit anti-FGL1 anticorps

Fonction: Recombinant FGL1 Monoclonal Antibody

Purification: Protein A purified

Immunogène: Recombinant human FGL1 fragment

Isotype: IgG, kappa

Information d'application

Indications d'application: WB 1:1000,IHC 1:50-1:200

Restrictions: For Research Use only

Stockage

Concentration: 1 mg/mL

Buffer: PBS, 50 % glycerol, 0.05 % Proclin 300, 0.05 % protein protectant.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

Date de péremption: 12 months

Détails sur FGL1

Antigène: FGL1 (Fibrinogen-Like 1 (FGL1))

Autre désignation: FGL1

Sujet: FGL,Fibrinogen-like protein,Liver fibrinogen-related protein,LFIRE,HP-041,Hepassocin,HPS,HFREP-1,LFIRE-1,HFREP1,Fibrinogen-like protein 1,Liver fibrinogen-related protein 1,FGL1,Fgl1,Hepassocin,HFREP1,HFREP-1,FGL 1,Fibrinogen like 1,Fibrinogen like protein 1,Fibrinogen related protein 1,Hepatocellular carcinoma related sequence,Hepatocyte derived fibrinogen related protein 1,Hepatocyte-derived fibrinogen-related protein 1,HFREP 1,HP 041,HP041,LFIRE 1,LFIRE1,Liver fibrinogen related protein 1,MFIRE 1,MGC108569,MGC12455,MGC37822,OTTHUMP00000122468,Fibrinogen-like protein 1 (FGL1), also known as hepassocin, is a secreted protein mainly expressed in liver and its expression is further enhanced following acute liver injury. FGL1 null mice have multiple metabolic abnormalities and are more prone to develop hepatocellular carcinoma under certain experimental conditions, suggesting FGL1 has diverse functions in vivo. More recently, FGL1 was found to be highly expressed in human cancer cells and function as an inhibitory ligand for LAG3. Blockade of the FGL1-LAG3 interaction stimulates tumor immunity in mouse models. In addition, a high plasma FGL1 level in human cancer patients is associated with a poor prognosis and resistance to anti-PD-1/PD-L1 immunotherapy. Cat.No. Product Name Clone No. IF:{{item.impact}} Journal:{{item.journal}} ({{item.year}}) DOI:{{item.doi}} Reactivity:{{item.species}} Sample Type:{{item.sample_type}} Previous {{ page }} Next Q{{(FAQpage.currentPage - 1)*pageSize+index+1}}:{{item.name}} Previous {{ page }} Next [

Poids moléculaire:

Calculated MW: 36 kDa

Observed MW: 34 kDa The actual band is not consistent with the expectation.

UniProt: Q08830