Recombinant Histone H4 anticorps (H4K12me1)

N° du produit ABIN7828285

Cet anticorps Lapin Monoclonal détecte spécifiquement Histone H4 dans WB, IHC, IF, IP, ChIP et FACS. Il présente une réactivité avec des échantillons de Humain, Souris et Rat.

Aperçu rapide pour Recombinant Histone H4 anticorps (H4K12me1) (ABIN7828285)

Antigène: Histone H4

Type d'anticorp: Recombinant Antibody

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Monoclonal

Conjugué: Cet anticorp Histone H4 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF), Immunoprecipitation (IP), Chromatin Immunoprecipitation (ChIP), Flow Cytometry (FACS)

Clone: A838

Détail du produit anti-Histone H4 anticorps

Épitope: H4K12me1

Fonction: Recombinant Histone H4 (Mono Methyl Lys12) Monoclonal Antibody

Purification: Protein A purified

Immunogène: Monomethylated human histone H4 (Lys12) peptide

Isotype: IgG, kappa

Information d'application

Indications d'application: WB 1:500-1:2000,IHC 1:100-1:500,IF 1:50-1:200,FCM 1:50,ChIP 6 μg/5x106 cells,IP 1:25-1:50

Restrictions: For Research Use only

Stockage

Concentration: 1 mg/mL

Buffer: PBS, 50 % glycerol, 0.05 % Proclin 300, 0.05 % protein protectant.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

Date de péremption: 12 months

Détails sur Histone H4

Antigène: Histone H4

Sujet: H4F,methyl histone H,methylated histone H,HIST2H,HIST1H,HISTH4H,histone H,HIST2H4B,H4/o,histone H4,HIST1H4A,FO108,H4/p,HIST1H4,Hist4h4,HISTH4H4,methyl histone H4,methylated histone H4,H4/A,H4FA,H4/I,H4FI,HIST1H4B,H4/G,H4FG,HIST1H4C,H4/B,H4FB,HIST1H4D,H4/J,H4FJ,HIST1H4E,H4/C,H4FC,HIST1H4F,H4/H,H4FH,HIST1H4H,H4/M,H4FM,HIST1H4I,H4/E,H4FE,H4/D,H4FD,HIST1H4K,H4/K,H4FK,HIST1H4L,H4/N,H4F2,H4FN,HIST2H4,HIST2H4A,H4,H4C1,H4C2,H4C3,H4C4,H4C5,H4C6,H4C8,H4C9,H4C11,H4C12,H4C13,H4C14,H4C15,H4-16,A,I,H4B,H4J,H4H,H4M,H4E,HIST1H4J,H4D,H4C,H4/p,histone H4,HIST1H4B H4/I,The amino-terminal tails of core histones undergo lysine methylation in multiple sites, termed as ""histone code"" or ""epigenetic code"". Lysine methylation in core histones is a major determinant for the formation of active and inactive regions of the genome and therefore plays vital roles in multiple cellular events. In most species, lysine methylation occurs primarily on histones H3 (Lys4, 9, 27, 36, 79) and H4 (Lys5, 8, 12, 20) and has been implicated in both transcriptional activation and silencing. Methylation in histones modulated by specific histone methyltransferases (HMTs) and histone demethylases (HDMs) is impaired in the pathologies of cancer and other diseases and therefore, enzymes regulating histone lysine methylation have become promising targets for anti-cancer drugs. Cat.No. Product Name Clone No. IF:{{item.impact}} Journal:{{item.journal}} ({{item.year}}) DOI:{{item.doi}} Reactivity:{{item.species}} Sample Type:{{item.sample_type}} Previous {{ page }} Next Q{{(FAQpage.currentPage - 1)*pageSize+index+1}}:{{item.name}} Previous {{ page }} Next [

Poids moléculaire:

Calculated MW: 11 kDa

Observed MW: 11 kDa

UniProt: P62805