Recombinant Monoamine Oxidase A anticorps
Aperçu rapide pour Recombinant Monoamine Oxidase A anticorps (ABIN7828399)
Antigène
Voir toutes Monoamine Oxidase A (MAOA) AnticorpsType d'anticorp
Reactivité
Hôte
Clonalité
Conjugué
Application
Clone
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Fonction
- Recombinant MAO-A Monoclonal Antibody
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Purification
- Protein A purified
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Immunogène
- Recombinant human MAO-A fragment
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Isotype
- IgG, kappa
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Indications d'application
- WB 1:500-1:1000,IHC 1:50-1:200
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Restrictions
- For Research Use only
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Concentration
- 1 mg/mL
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Buffer
- PBS, 50 % glycerol, 0.05 % Proclin 300, 0.05 % protein protectant.
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Agent conservateur
- ProClin
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Précaution d'utilisation
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Stock
- -20 °C
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Stockage commentaire
- Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
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Date de péremption
- 12 months
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- Monoamine Oxidase A (MAOA)
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Autre désignation
- MAO-A
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Sujet
- MAOA,BRNRS,MAO-A,Monoamine oxidase A (MAO-A), a mitochondrial enzyme, catalyzes the degradation of monoamines. Studies show that increased expression of MAO-A promotes prostate cancer metastasis by activating the Shh-IL6-RANKL signaling network. In addition, MAO-A expression in adipose tissue macrophages is upregulated in aging, leading to the reduction of noradrenaline availability in adipose tissue. Decreased levels of noradrenaline contribute to the aging-related decline of catecholamine-induced lipolysis in adipocytes. Furthermore, sympathetic neuron-associated macrophages import and degrade norepinephrine via the transporter SLC6A2 and MAO-A, respectively, and thus contribute to obesity. Cat.No. Product Name Clone No. IF:{{item.impact}} Journal:{{item.journal}} ({{item.year}}) DOI:{{item.doi}} Reactivity:{{item.species}} Sample Type:{{item.sample_type}} Previous {{ page }} Next Q{{(FAQpage.currentPage - 1)*pageSize+index+1}}:{{item.name}} Previous {{ page }} Next [
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Poids moléculaire
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Calculated MW: 60 kDa
Observed MW: 60 kDa
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UniProt
- P21397
Antigène
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