Recombinant MUC1 anticorps

N° du produit ABIN7828401

Cet anticorps anti-MUC1 Monoclonal Lapin (Clone A309) (ABIN7828401) détecte spécifiquement MUC1 dans IHC et WB. L’anticorps est réactif avec des échantillons de Humain, Souris et Rat.

Aperçu rapide pour Recombinant MUC1 anticorps (ABIN7828401)

Antigène: MUC1 (Mucin 1 (MUC1))

Type d'anticorp: Recombinant Antibody

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Monoclonal

Conjugué: Cet anticorp MUC1 est non-conjugé

Application: Immunohistochemistry (IHC), Western Blotting (WB)

Clone: A309

Détail du produit anti-MUC1 anticorps

Fonction: Recombinant MUC1 Monoclonal Antibody

Purification: Protein A purified

Immunogène: Recombinant human MUC1 fragment

Isotype: IgG, kappa

Information d'application

Indications d'application: WB 1:500-1:1000,IHC 1:200-1:1000

Restrictions: For Research Use only

Stockage

Concentration: 1 mg/mL

Buffer: PBS, 50 % glycerol, 0.05 % Proclin 300, 0.05 % protein protectant.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

Date de péremption: 12 months

Détails sur MUC1

Antigène: MUC1 (Mucin 1 (MUC1))

Autre désignation: MUC1

Sujet: MAM,CA 15,MUC,ADMCKD,ADMCKD1,CA 15-3,CD227,EMA,H23AG,KL-6,MAM6,MCD,MCKD,MCKD1,MUC-1,MUC-1/SEC,MUC-1/X,MUC1/ZD,PEM,PEMT,PUM,MUC1,CA15-3,mucin-1,CA15 3,CA153,Episialin,Carcinoma associated mucin,MUC 1,MUC1 beta,MUC1 CT,MUC1 NT,Mucin 1,Peanut reactive urinary mucin,Polymorphic epithelial mucin,Tumor associated mucin,MUC1/CA15-3 C-terminal,EMA,mucin 1,Breast carcinoma-associated antigen DF3,Cancer antigen 15-3,Carcinoma-associated mucin,Krebs von den Lungen-6,Peanut-reactive urinary mucin,Tumor-associated epithelial membrane antigen,Tumor-associated mucin,The alpha subunit has cell adhesive properties. Can act both as an adhesion and an anti-adhesion protein. May provide a protective layer on epithelial cells against bacterial and enzyme attack.The beta subunit contains a C-terminal domain which is involved in cell signaling, through phosphorylations and protein-protein interactions. Modulates signaling in ERK, SRC and NF-kappa-B pathways. In activated T-cells, influences directly or indirectly the Ras/MAPK pathway. Promotes tumor progression. Regulates TP53-mediated transcription and determines cell fate in the genotoxic stress response. Binds, together with KLF4, the PE21 promoter element of TP53 and represses TP53 activity. Cat.No. Product Name Clone No. IF:{{item.impact}} Journal:{{item.journal}} ({{item.year}}) DOI:{{item.doi}} Reactivity:{{item.species}} Sample Type:{{item.sample_type}} Previous {{ page }} Next Q{{(FAQpage.currentPage - 1)*pageSize+index+1}}:{{item.name}} Previous {{ page }} Next [

Poids moléculaire:

Calculated MW: 17 kDa

Observed MW: 24 kDa The actual band is not consistent with the expectation.

UniProt: P15941

Pathways: Negative Regulation of intrinsic apoptotic Signaling