Recombinant PAX8 anticorps

N° du produit ABIN7828439

L’anticorps anti-PAX8 Monoclonal Lapin est utilisé pour la détection de PAX8 dans des échantillons de Humain, Souris et Rat. Il a été validé pour IHC et IF.

Aperçu rapide pour Recombinant PAX8 anticorps (ABIN7828439)

Antigène: PAX8 (Paired Box 8 (PAX8))

Type d'anticorp: Recombinant Antibody

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Monoclonal

Conjugué: Cet anticorp PAX8 est non-conjugé

Application: Immunohistochemistry (IHC), Immunofluorescence (IF)

Clone: A323

Détail du produit anti-PAX8 anticorps

Fonction: Recombinant PAX8 Monoclonal Antibody

Purification: Protein A purified

Immunogène: Recombinant human PAX8 fragment

Isotype: IgG, kappa

Information d'application

Indications d'application: IHC 1:50-1:100,IF 1:50

Restrictions: For Research Use only

Stockage

Concentration: 1 mg/mL

Buffer: PBS, 50 % glycerol, 0.05 % Proclin 300, 0.05 % protein protectant.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

Date de péremption: 12 months

Détails sur PAX8

Antigène: PAX8 (Paired Box 8 (PAX8))

Autre désignation: PAX8

Sujet: Paired box,Paired box gene,Paired domain gene,paired box homeotic gene,PAX,PAX8,OTTHUMP00000158659,OTTHUMP00000158660,OTTHUMP00000203723,OTTHUMP00000203724,Paired box 8,Paired box gene 8,paired box homeotic gene 8,Paired box protein Pax 8,Paired box protein Pax-8,Paired domain gene 8,PAX 8,PAX8 is one of nine transcription factors within the PAX gene family. It has been observed to be expressed during embryonic development however expression attenuates after development in all but a few tissues. Research has indicated that over-expression of PAX proteins in general are not an initiating event in tumorgenesis however they may facilitate malignant development. PAX8 is expressed in 80-96 % of all High-grade serous carcinomas (HGSC) and is commonly used as a marker for the disease. In addition PAX8 has become a useful biomarker for differentiating between mullerian mucinous and non-mullerian tumors. PAX8 has also been associated with neoplasms in the kidney and thyroid. Cat.No. Product Name Clone No. IF:{{item.impact}} Journal:{{item.journal}} ({{item.year}}) DOI:{{item.doi}} Reactivity:{{item.species}} Sample Type:{{item.sample_type}} Previous {{ page }} Next Q{{(FAQpage.currentPage - 1)*pageSize+index+1}}:{{item.name}} Previous {{ page }} Next [

UniProt: Q06710

Pathways: Thyroid Hormone Synthesis, Regulation of Hormone Metabolic Process, Stem Cell Maintenance, Tube Formation