Recombinant PEG10 anticorps
Aperçu rapide pour Recombinant PEG10 anticorps (ABIN7828446)
Antigène
Voir toutes PEG10 AnticorpsType d'anticorp
Reactivité
Hôte
Clonalité
Conjugué
Application
Clone
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Fonction
- Recombinant PEG10 Monoclonal Antibody
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Purification
- Protein A purified
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Immunogène
- Recombinant human PEG10 fragment
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Isotype
- IgG, kappa
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Indications d'application
- WB 1:500-1:1000
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Restrictions
- For Research Use only
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Concentration
- 1 mg/mL
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Buffer
- PBS, 50 % glycerol, 0.05 % Proclin 300, 0.05 % protein protectant.
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Agent conservateur
- ProClin
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Précaution d'utilisation
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Stock
- -20 °C
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Stockage commentaire
- Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
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Date de péremption
- 12 months
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- PEG10 (Paternally Expressed 10 (PEG10))
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Autre désignation
- PEG10
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Sujet
- PEG,RTL,Mart,RGAG,SIRH,KIAA,PEG10,EDR,HB-1,MEF3L,2-Mar,Mart2,RGAG3,RTL2,SIRH1,KIAA1051,MEF3L1,Paternally expressed gene 10(PEG10 ) is an imprinted gene which is derived from a Ty3/Gypsy long terminal repeat (LTR) retrotransposon family encoding Gag- and Pol-like domains. Deletion of PEG10 in mice leads to embryonic lethality due to defects in placental formation. PEG10 is aberrantly expressed in several cancer types, including hepatocellular carcinoma, and contributes to tumorigenesis by affecting cell proliferation, apoptosis, and metastasis. The PEG10 gene has two overlapping open reading frames that are regulated by the programmed process of -1 frameshifting. The first encoded protein ORF1 (or RF1) has a Gag domain with coiled-coil domain and zinc finger domains, while ORF1-2 (or RF1/RF2) is produced by -1 frameshifting and creates a fusion of the ORF1 Gag domain with a carboxyl-terminal Pol-like protease domain. PEG10 has retained the ability to form virus-like particles (VLPs) that are secreted as small extracellular vesicles delivered to distant sites. Cat.No. Product Name Clone No. IF:{{item.impact}} Journal:{{item.journal}} ({{item.year}}) DOI:{{item.doi}} Reactivity:{{item.species}} Sample Type:{{item.sample_type}} Previous {{ page }} Next Q{{(FAQpage.currentPage - 1)*pageSize+index+1}}:{{item.name}} Previous {{ page }} Next [
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Poids moléculaire
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Calculated MW: 55/100 kDa
Observed MW: 55/100 kDa
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UniProt
- Q86TG7
Antigène
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