Recombinant PLAG1 anticorps

N° du produit ABIN7828465

Cet anticorps Lapin Monoclonal détecte spécifiquement PLAG1 dans WB et IHC. Il présente une réactivité avec des échantillons de Humain, Souris et Rat.

Aperçu rapide pour Recombinant PLAG1 anticorps (ABIN7828465)

Antigène: PLAG1 (Pleiomorphic Adenoma Gene 1 (PLAG1))

Type d'anticorp: Recombinant Antibody

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Monoclonal

Conjugué: Cet anticorp PLAG1 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Clone: A660

Détail du produit anti-PLAG1 anticorps

Fonction: Recombinant PLAG1 Monoclonal Antibody

Purification: Protein A purified

Immunogène: Recombinant human PLAG1 fragment

Isotype: IgG, kappa

Information d'application

Indications d'application: WB 1:5000-1:10000,IHC 1:50

Restrictions: For Research Use only

Stockage

Concentration: 1 mg/mL

Buffer: PBS, 50 % glycerol, 0.05 % Proclin 300, 0.05 % protein protectant.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

Date de péremption: 12 months

Détails sur PLAG1

Antigène: PLAG1 (Pleiomorphic Adenoma Gene 1 (PLAG1))

Autre désignation: PLAG1

Sujet: ZNF,Zinc finger protein PLAG,Pleiomorphic adenoma gene,FGFR1/PLAG1 fusion variant,PLAG,COL1A2/PLAG1 fusion,FGFR1/PLAG1 fusion variant 3,Pleiomorphic adenoma gene 1,Pleiomorphic adenoma gene 1 protein,PSA,SGPA,Zinc finger protein PLAG1,ZNF912,PLAG1,PSA,SGPA,Pleiomorphic adenoma gene 1 protein (PLAG1) is a transcription factor whose activation results in up-regulation of target genes, such as IGFII, leading to uncontrolled cell proliferation. When PLAG1 overexpression in cultured cells, higher proliferation rate and transformation are observed. Other target genes such as CRLF1, CRABP2, CRIP2, PIGF are strongly induced in cells with PLAG1 induction. PLAG1 ectopic expression can trigger the development of pleomorphic adenomas of the salivary gland and lipoblastomas. PLAG1 overexpression is associated with up-regulation of IGFII, is frequently observed in hepatoblastoma, common primary liver tumor in childhood. PLAG1 cooperates with CBFB-MYH11, a fusion gene important for myeloid leukemia. Cat.No. Product Name Clone No. IF:{{item.impact}} Journal:{{item.journal}} ({{item.year}}) DOI:{{item.doi}} Reactivity:{{item.species}} Sample Type:{{item.sample_type}} Previous {{ page }} Next Q{{(FAQpage.currentPage - 1)*pageSize+index+1}}:{{item.name}} Previous {{ page }} Next [

Poids moléculaire:

Calculated MW: 56 kDa

Observed MW: 56 kDa

UniProt: Q6DJT9