Recombinant PCGF5 anticorps
Aperçu rapide pour Recombinant PCGF5 anticorps (ABIN7828467)
Antigène
Voir toutes PCGF5 AnticorpsType d'anticorp
Reactivité
Hôte
Clonalité
Conjugué
Application
Clone
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Fonction
- Recombinant PCGF5 Monoclonal Antibody
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Purification
- Protein A purified
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Isotype
- IgG, kappa
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Indications d'application
- WB 1:1000
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Restrictions
- For Research Use only
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Concentration
- 1 mg/mL
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Buffer
- PBS, 50 % glycerol, 0.05 % Proclin 300, 0.05 % protein protectant.
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Agent conservateur
- ProClin
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Précaution d'utilisation
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Stock
- -20 °C
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Stockage commentaire
- Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
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Date de péremption
- 12 months
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- PCGF5 (Polycomb Group Ring Finger 5 (PCGF5))
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Autre désignation
- PCGF5
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Sujet
- RNF,Pcgf,RNF159,PCGF5,PCGF5 is the omponent of a Polycomb group (PcG) multiprotein PRC1-like complex, a complex class required to maintain the transcriptionally repressive state of many genes, including Hox genes, throughout development. PcG PRC1 complex acts via chromatin remodeling and modification of histones, it mediates monoubiquitination of histone H2A 'Lys-119', rendering chromatin heritably changed in its expressibility.Within the PRC1-like complex, PCGF5 regulates RNF2 ubiquitin ligase activity. PCGF5 plays a redundant role with PCGF3 as part of a PRC1-like complex that mediates monoubiquitination of histone H2A 'Lys-119' on the X chromosome and is required for normal silencing of one copy of the X chromosome in XX females. Cat.No. Product Name Clone No. IF:{{item.impact}} Journal:{{item.journal}} ({{item.year}}) DOI:{{item.doi}} Reactivity:{{item.species}} Sample Type:{{item.sample_type}} Previous {{ page }} Next Q{{(FAQpage.currentPage - 1)*pageSize+index+1}}:{{item.name}} Previous {{ page }} Next [
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Poids moléculaire
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Calculated MW: 30 kDa
Observed MW: 30 kDa
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UniProt
- Q86SE9
Antigène
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